YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: twf-PA
Organism: Drosophila melanogaster
Length: 343 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for twf-PA.

Description E-value Query
Range
Subject
Range
gi|48145581 - gi|48145581|emb|CAG33013.1| PTK9L [Homo sapiens]
382.0 [0..1] [343..1]

Back

Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHQTGIRAN EQLAKVFGKA KNGKFRVIKV SIENEQLSCG ATAETKKDWE RDYDKLIGPL  60
   61 LEKDVPCYIL YRLDAKIPLG YSWLLISWTP DTASIRQKMV YASTKATLKT EFGSAYITEE 120
  121 LHATTLDECT LEGYRRHKQD FA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 1m4jA
Description: Adf-H domain of twinfilin isoform-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.52071741004022 bayes_pls_golite062009
cytoskeletal protein binding 6.04859625643932 bayes_pls_golite062009
actin filament binding 5.45532510538573 bayes_pls_golite062009
binding 2.41877859618486 bayes_pls_golite062009
protein kinase activity 2.22634235673758 bayes_pls_golite062009
protein binding 1.87981807141519 bayes_pls_golite062009
protein tyrosine kinase activity 1.87091423399482 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.67227267699496 bayes_pls_golite062009
kinase activity 1.55883505515498 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.3406661967545 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.30213296029859 bayes_pls_golite062009
molecular transducer activity 1.14209355225632 bayes_pls_golite062009
signal transducer activity 1.14209355225632 bayes_pls_golite062009
transferase activity 0.591259446255369 bayes_pls_golite062009
structural constituent of cytoskeleton 0.482954032096802 bayes_pls_golite062009
structural molecule activity 0.391701411061931 bayes_pls_golite062009
actin monomer binding 0.224304003054399 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [143-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APAPLTSREE ELKELRKTEV HTEINTNTRH QTLGGINCPL SEATVAAVQD LVRGKHDYLQ  60
   61 FRIDLEEEQI HVSRAAKVEL ADLPKQVPED HARYHLFLFR HTHEGDYFES YVFVYSMPGY 120
  121 SCSVRERMMY SSCKAPFLDE LAALGVEVVK KLEIDSGSEL TEAFLQDELH PKKILHRPAF 180
  181 AKPKGPPNRG AKRLTRPTAE D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 2d8bA
Description: No description for 2d8bA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle