YRC Public Data Repository - Protein Structure Prediction

Protein:	GstD2-PA
Organism:	Drosophila melanogaster
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GstD2-PA.

Description	E-value	Query Range	Subject Range
GstD5-PA - The gene Glutathione S transferase D5 is referred to in FlyBase by the symbol Dmel\GstD5 (CG12242, F...	184.0	[0..1]	[215..1]
GST1C_ANOGA - Glutathione S-transferase 1, isoform C OS=Anopheles gambiae GN=GstD1 PE=1 SV=2 gi\|31208165, gi\|... - gi\|31208165\|ref\|XP_313049.1\| glutathione transferase (AGAP004164-PA) [Anopheles gambiae str. PEST], ...	180.0	[0..1]	[209..1]
gi\|22218856, gi\|... - gi\|22218860\|pdb\|1JLV\|F Chain F, Anopheles Dirus Species B Glutathione S-Transferases 1-3, gi\|2221885... gi\|11596150 - gi\|11596150\|gb\|AAG38505.1\| glutathione transferase GST1-3 [Anopheles dirus]	179.0	[0..1]	[209..1]
GSTT5_ANOGA, GTT... - (Q93112) Glutathione S-transferase 1-5 (EC 2.5.1.18) (GST class-theta), (Q93112) Glutathione S-trans...	178.0	[0..1]	[209..1]
gi\|125773523, gi... - gi\|54637755\|gb\|EAL27157.1\| GA18009-PA [Drosophila pseudoobscura], gi\|125773523\|ref\|XP_001358020.1\| G...	177.0	[0..1]	[215..2]
GSTT1_MUSDO - Glutathione S-transferase 1 OS=Musca domestica GN=Gst1 PE=2 SV=1	177.0	[0..1]	[207..1]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFYYMPGGG GCRTVIMVAK ALGLELNKKL LNTMEGEQLK PEFVKLNPQH TIPTLVDNGF  60
   61 SIWESRAIAV YLVEKYGKDD YLLPNDPKKR AVINQRLYFD MGTLYESFAK YYYPLFRTGK 120
  121 PGSDEDLKRI ETAFGFLDTF LEGQEYVAGD QLTVADIAIL STVSTFEVSE FDFSKYSNVS 180
  181 RWYDNAKKVT PGWDENWEGL MAMKALFDAR KLAAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.39794
Match:	1jlvA
Description:	Class delta GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
glutathione binding	2.07086805531749	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
glutathione transferase activity	1.85683051472829	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
selenium binding	1.57446915214149	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	0.704132579378598	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
receptor binding	0.0226227421058591	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: