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View Structure Prediction Details

Protein: CG31116-PD
Organism: Drosophila melanogaster
Length: 1193 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31116-PD.

Description E-value Query
Range
Subject
Range
CG31116-PA - This gene is referred to in FlyBase by the symbol Dmel\CG31116 (CG31116, FBgn0051116). It is a prote...
881.0 [0..14] [1193..3]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYFGDRQRD RNRDRSNQKV ERIIHDEEFG EENVELVDSE WADFEKFICQ LRKRRNSAMS  60
   61 MEEELRHVQR HPKIKSHAFY PCPPPAENAR DSDSSDDDDP IGYIDTLMYG RYTKDLGEFA 120
  121 KDEARKLKIL EKRRKQEDKQ RNKELLG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [148-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHSTRAKRVS SWIWRHTVAR LGEDWVFLAL LGIIMALLSF IMDKGISICT NARIWLYRDL  60
   61 TSQPFVQYIA WVSLPVCLIL FSAGFVHLIA PQSIGSGIPE MKTILRGVQL KEYLTFKTLV 120
  121 AKVIGLTATL GSGMPLGKEG PFVHIASIVA QLLSKLVTSF QGIYENESRN SEMLAAACAV 180
  181 GVGACFAAPV GGVLFSIEVT TTYFAVRNYW RGFFAAVCGA TVFRLLAVWF QNADTVRALF 240
  241 LTNFTTEFPF DPQELFVFAL IGLVCGLGGA SYVWVHRRYV LFMRSNKRMN KFLQKNRFLY 300
  301 PGFLALLVSS ISFPLGTGQF LAGELSTHEQ VTQLFSNFTW SRDDLTVEQA AVVTHWMTSY 360
  361 TSVFGNLVIY TLFTFVVSII ASTIPVPSGM FIPVFKIGAG FGRLVGEFMA VTFPHGVRYG 420
  421 G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 119.0
Match: 1bccC
Description: Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ion transmembrane transporter activity 5.40841877729638 bayes_pls_golite062009
cation transmembrane transporter activity 5.07397778974763 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.00837716908852 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 4.73782014776765 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 4.30670554972234 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.19248725934065 bayes_pls_golite062009
transporter activity 3.45764306673522 bayes_pls_golite062009
transmembrane transporter activity 3.37175230596465 bayes_pls_golite062009
substrate-specific transporter activity 3.1315645069307 bayes_pls_golite062009
electron carrier activity 1.22860504916385 bayes_pls_golite062009
binding 1.14367469001261 bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity 0.457303833709505 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 0.457303833709505 bayes_pls_golite062009
protein binding 0.404482007264961 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 0.112640991733972 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [569-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLSPIMPGGY AVVGAAAFSG SVTHTVSVAV IIFEMTGQIT HVVPVMIAVL VANAVAALLQ  60
   61 PSIYDSIILI KKLPYLPDL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.53
Match: 1kplA
Description: Clc chloride channel
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [648-877]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSSSGMYSI FVEDFMVRDV KYIWHGISYQ KLKEVLKLNK TLRSLPLVDS PDNMILLGSV  60
   61 QRYELIKMIE KHIGREKRME VAQKWQKEAQ ERALEEEKKK QEVELKMRRP SRFEVLPAPD 120
  121 ILSLRQIAND EMLPPKKRAE TMHGSLAPRK SILKKTNSFN LKTYAQPMGH SPSITPYTTI 180
  181 TGNSEFRIRS AFEAIFKKST TLQDVQPDPE TGSLSPAASN HEVEVPRTPS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2d4zA
Description: Crystal structure of the cytoplasmic domain of the chloride channel ClC-0
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [878-974]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPGVSKKVQL PAQSNWDFVT DQIMLQVNPI STESNKMPAE KDFTDKALSN NGDSSKQSPS  60
   61 IKFKANKVAD VNRSPQTAKR CSKIRFANEV GVNGSPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [975-1114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTKCKIKPEN VLGYSIEDVD ETTNPESLAE SIQKPKSVRL PRERVIDMSP EDQKQWELEE  60
   61 MLKPIDLQKA NVHIDPSPFQ LVERTSILKV HSLFSMVGIN HAYVTKIGRL VGVVGLKELR 120
  121 KAIEDINSNS FVPPTRDEDA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.045757
Match: 2pfiA
Description: No description for 2pfiA was found.

Predicted Domain #7
Region A:
Residues: [1115-1193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKPAVEKPL LSTNSSDKAV DMTVTSMDSA LSNSENCSDI EMEHIKHTDK GTVSLTMPPQ  60
   61 ESKQSPSADK SNTENGNHA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle