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View Structure Prediction Details

Protein: tomboy20-PA
Organism: Drosophila melanogaster
Length: 147 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tomboy20-PA.

Description E-value Query
Range		 Subject
Range
TOM20_MOUSE - Mitochondrial import receptor subunit TOM20 homolog OS=Mus musculus GN=Tomm20 PE=1 SV=1
TOM20_RAT - Mitochondrial import receptor subunit TOM20 homolog OS=Rattus norvegicus GN=Tomm20 PE=1 SV=2
 195.0 [0..4] [142..2]
gi|48145553 - gi|48145553|emb|CAG32999.1| TOMM20 [Homo sapiens]
 195.0 [0..4] [142..2]
gi|1838935 - gi|1838935|dbj|BAA09714.1| mitochondrial precursor receptor [Rattus sp.]
 194.0 [0..4] [142..2]
gi|76676674 - gi|76676674|ref|XP_870365.1| PREDICTED: similar to Mitochondrial import receptor subunit TOM20 homol...
 193.0 [0..4] [142..2]
TOM20_RAT, OM20_RAT - Mitochondrial import receptor subunit TOM20 homolog - Rattus norvegicus (Rat), (Q62760) Mitochondria...
 192.0 [0..4] [142..2]
gi|50797812 - gi|50797812|ref|XP_423972.1| PREDICTED: similar to Mitochondrial import receptor subunit TOM20 homol...
 192.0 [0..4] [142..75]
TOM20_XENLA - Mitochondrial import receptor subunit TOM20 homolog OS=Xenopus laevis GN=tomm20 PE=2 SV=1
 192.0 [0..1] [142..1]
TOM20_XENTR - Mitochondrial import receptor subunit TOM20 homolog OS=Xenopus tropicalis GN=tomm20 PE=2 SV=1
 191.0 [0..1] [142..1]
gi|109085461 - gi|109085461|ref|XP_001094304.1| PREDICTED: translocase of outer mitochondrial membrane 20 homolog (...
 191.0 [0..4] [142..2]

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Predicted Domain #1
Region A:
Residues: [1-147] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGVSGTFKV LAAISGILFM GYCVYFDKQR RSDPDFKRKL HERRIQRSLA SVKSTASVSM  60
   61 SERDVEVYFM TQIHKGETLI TNGDVEAGVE HLINAILVCG QPSKLLQLLQ STLPMDIFTT 120
  121 MLIKMHAYEA SQRCLPVLVD DEATSSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1om2A
Description: Mitochondrial import receptor subunit Tom20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 3.40898729129243 bayes_pls_golite062009
macromolecule transmembrane transporter activity 3.40898729129243 bayes_pls_golite062009
protein transmembrane transporter activity 2.85488085984023 bayes_pls_golite062009
protein transporter activity 2.05250883327513 bayes_pls_golite062009
transporter activity 1.79559401386194 bayes_pls_golite062009
binding 1.66795187393523 bayes_pls_golite062009
transmembrane transporter activity 1.6303525042646 bayes_pls_golite062009
substrate-specific transporter activity 1.49267876312697 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.3436996680931 bayes_pls_golite062009
protein binding 1.10534436186662 bayes_pls_golite062009
primary active transmembrane transporter activity 1.0671316259706 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.06141451496527 bayes_pls_golite062009
active transmembrane transporter activity 1.01882616059722 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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