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View Structure Prediction Details

Protein: osk-PA
Organism: Drosophila melanogaster
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for osk-PA.

Description E-value Query
Range
Subject
Range
gi|54639252, gi|... - gi|54639252|gb|EAL28654.1| GA10627-PA [Drosophila pseudoobscura], gi|125777137|ref|XP_001359508.1| G...
488.0 [0..27] [606..1]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVTSEFPS KPISYTSTNT SAKTYYLKSV KKRVTTCFQQ LRDKLQSSGS FRKSSSSCLN  60
   61 QIFVRSDFSA CGERFRKIFK SARKTELPEL WKVPLVAHEL TSRQSSQQLQ VVARLFSSTQ 120
  121 ISTKEITYNS NSNTSENNMT IIE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [144-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNYISVREEY PDIDSEVRAI LLSHAQNGIT ISSIKSEYRK LTGNPFPLHD NVTDFLLTIP  60
   61 NVTAECSESG KRIFNLKASL KNGHLLDMVL NQKERTSDYS SGAPSLENIP RAPPRYWKNP 120
  121 FKRRALSQLN TSPRTVPKIT DEKTKDIATR PVSLHQMANE AAESNWCYQD NWKHLNNFYQ 180
  181 QASVNA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [330-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKMPVPINIY SPDAPEEPIN LAPPGHQPSC RTQSQKTEPT ENRHLGIFVH PFNGMNIMKR  60
   61 RHEMTPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [397-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTILTSGTYN DSLLTINSDY DAYLLDFPLM GDDFMLYLAR MELKCRFRRH ERVLQSGLCV  60
   61 SGLTINGARN RLKRVQLPEG TQIIVNIGSV DIMRGKPLVQ IEHDFRLLIK EMHNMRLVPI 120
  121 LTNLAPLGNY CHDKVLCDKI YRFNKFIRSE CCHLKVIDIH SCLINERGVV RFDCFQASPR 180
  181 QVTGSKEPYL FWNKIGRQRV LQVIETSLEY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.045757
Match: 1jrlA
Description: Thioesterase I, TAP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.5922433129317 bayes_pls_golite062009
binding 1.48824074563071 bayes_pls_golite062009
catalytic activity 1.15974340242656 bayes_pls_golite062009
hydrolase activity 0.45071330223777 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0322595213897547 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle