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View Structure Prediction Details

Protein: FBpp0293837
Organism: Drosophila melanogaster
Length: 1149 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293837.

Description E-value Query
Range
Subject
Range
FBpp0293838 - type=protein; loc=3R:complement(4654037..4654040,4657864..4657996,4658076..4658367,4658426..4658666,...
646.0 [0..1] [1149..1]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFPDYVPNN MLVGDRTTWE YHTVAVTRVP GYGFGIAVSG GRDNPHFANG DPSIAVSDVL  60
   61 KGGPAEDRLQ VNDRIISVNG VSLENVEYAT AVQVLRDSGN TVQLVVKRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.09691
Match: 2h2bA
Description: No description for 2h2bA was found.

Predicted Domain #2
Region A:
Residues: [110-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPLNPINAAG AVQHQHSHSL SSVGLMANGS GGVAPTPITS LSQPNSLNSS LVQNASSGQP  60
   61 IKVTLTKGGK KDDYGVVLGC RLFVKEISSK AREQLNANGY SLQEGDIITR IHNTNCGDTM 120
  121 SLKEAKKIID GCKERLNLVV LRDITNQTAV SQLNLNNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 2osgA
Description: No description for 2osgA was found.

Predicted Domain #3
Region A:
Residues: [268-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASHQASGNIY ATHQPQVSGC SSSNNNLEDP YLPGGASYSS QNLYVQPPTR TSNGPNINGN  60
   61 GLNDEKSNLT PRGRSRGPIM DGVSLQQLDR PVTPTRGRSA AIDEPPRPPP PRGSSGGAAQ 120
  121 EDFYSSRRQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [397-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYEERQSAEP RFISFQKEGS VGIRLTGGNE AGIFVTAVQP GSPASLQGLM PGDKILKVND  60
   61 MDMNGVTREE AVLFLLSLQD RIDLIVQYCK EEYDEVVTNQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1tp3A
Description: PDZ3 domain of PSD-95 protein complexed with KKETPV peptide ligand
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [497-799]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGDSFHIKTH FHCDNPSKGE MAFKAGDVFR VIDTLHNGVV GSWQVLKIGR GHQEMQRGVI  60
   61 PNKSRAEELA TAQFNATKKE MNANESRGNF FRRRRSTHRR SKSLSRENWD DVVFSDSISK 120
  121 FPAYERVVLR HPGFVRPVVL FGPVSDLARE RLAKDFPDKF STPLQDDDKS AATSGKCRIV 180
  181 RLSNIRDVMD RGKHALLDIT PNAVDRLNYA QFYPVVIFLK TDSKHVIKQL RHGLPKAAHK 240
  241 SSKKLLEQCQ KLERVWSHIF STQIALSDEE SWYRKLRDSI DLQQSGAVWM SESKPVESLS 300
  301 DDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.045757
Match: 1kjwA
Description: Psd-95; Guanylate kinase-like domain of Psd-95
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [800-901]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFPMTTSRLS YASSPESDLE LSPGPSASLS LGNLPQLVKA SSDPSIATNQ DNLDRDRDII  60
   61 GEGLPPPYTV PYDHAVPANP NRRQTMDSSK YSIYGTNVPP QQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [902-1149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQPGVGGDTA AVRPQSLYGI NAPDLPPRID RQSKPGDIPL NTSGSSSRNG TLGRSAQERL  60
   61 FGKAVVQDDV QAEYITRNAL VGSGAAETLD RQQQQQQQTH ASLERQARLN AQLKANGVGA 120
  121 GGGGASTYDS VSSYDSYNNT QMAMQNLGRL GPNAPDDLKS VPNANGRPLP PTGQSHEYGR 180
  181 TPHDHRSFGG PNDLNRQSSP GRPHYHDMNA SRNIDPRNGT PQRPSNLGLE SSPRKPLVET 240
  241 KTDYGKYS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle