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View Structure Prediction Details

Protein: FBpp0293840
Organism: Drosophila melanogaster
Length: 2090 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293840.

Description E-value Query
Range
Subject
Range
gi|15292241 - gi|15292241|gb|AAK93389.1| LD43161p [Drosophila melanogaster]
929.0 [0..5] [788..176]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFPDYVPNN MLVGDRTTWE YHTVAVTRVP GYGFGIAVSG GRDNPHFANG DPSIAVSDVL  60
   61 KGGPAEDRLQ VNDRIISVNG VSLENVEYAT AVQVLRDSGN TVQLVVKRRV PL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.39794
Match: 2h3mA
Description: No description for 2h3mA was found.

Predicted Domain #2
Region A:
Residues: [113-262]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPINAAGAVQ HQHSHSLSSV GLMANGSGGV APTPITSLSQ PNSLNSSLVQ NASSGQPIKV  60
   61 TLTKGGKKDD YGVVLGCRLF VKEISSKARE QLNANGYSLQ EGDIITRIHN TNCGDTMSLK 120
  121 EAKKIIDGCK ERLNLVVLRD ITNQTAVSQL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 2rczA
Description: No description for 2rczA was found.

Predicted Domain #3
Region A:
Residues: [263-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLNNSASHQA SGNIYATHQP QVSGCSSSNN NLEDPYLPGG ASYSSQNLYV QPPTRTSNGP  60
   61 NINGNGLNDE KSNLTPRGRS RGPIMDGVSL QQLDRPVTPT RGRSAAIDEP PRPPPPRGSS 120
  121 GGAAQEDFYS SRRQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [398-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEERQSAEPR FISFQKEGSV GIRLTGGNEA GIFVTAVQPG SPASLQGLMP GDKILKVNDM  60
   61 DMNGVTREEA VLFLLSLQDR IDLIVQYCKE EYDEVVT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.30103
Match: 1tp3A
Description: PDZ3 domain of PSD-95 protein complexed with KKETPV peptide ligand
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [495-780]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQRGDSFHIK THFHCDNPSK GEMAFKAGDV FRVIDTLHNG VVGSWQVLKI GRGHQEMQRG  60
   61 VIPNKSRAEE LATAQFNATK KEMNANESRG NFFRRRRSTH RRSKSLSREN WDDVVFSDSI 120
  121 SKFPAYERVV LRHPGFVRPV VLFGPVSDLA RERLAKDFPD KFSTPLQDDD KSAATSGKCR 180
  181 IVRLSNIRDV MDRGKHALLD ITPNAVDRLN YAQFYPVVIF LKTDSKHVIK QLRHGLPKAA 240
  241 HKSSKKLLEQ CQKLERVWSH IFSTQIALSD EESWYRKLRD SIDLQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.0
Match: 1kjwA
Description: Psd-95; Guanylate kinase-like domain of Psd-95
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [781-1715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGAVWMSESK VPYDHAVPAN PNRRQTMDSS KYSIYGTNVP PQQQQPGVGG DTAAVRPQSL  60
   61 YGINAPDLPP RIDRQSKPGD IPLNTSGSSS RNGTLGRSAQ ERLFGKAVVQ DDVQAEYITR 120
  121 NALVGSGAAE TLDRQQQQQQ QTHASLERQA RLNAQLKANG VGAGGGGAST YDSVSSYDSY 180
  181 NNTQMAMQNL GRLGPNAPDD LKSVPNANGR PLPPTGQSHE YGRTPHDHRS FGGPNDLNRQ 240
  241 SSPGRPHYHD MNASRNIDPR NGTPQRPSNL GLESSPRKPL VETKTDYGKY SRNNSVTQAD 300
  301 YTKLPKTAPH GVVPPPNVSN GQGQMNGSGT PSSNGSGPFK PVPPPKPKNY RPPVQSGGSS 360
  361 GSGGTTPWEN GDSGSPRSPN GFYYPPTPSH HHYGQQATPG SPSNGHMQPP PPQQQQPTYG 420
  421 GSNGNYGQAP PPQSYPQANG YNGNGHHYNG GSGTGPYIAP HRGMPPPIGN LPPHTPERHA 480
  481 LDLAGSREQR GSAFELYRKP QIGATAGHHH NMSEMEPYDE RYDDYYNMPP PAAHPSQGHH 540
  541 MQRSRSAPRY PHERPPHAQD PNYYGHYGTS RGHSQPRQQY SQHHQQQYYD DHGLEMGPPP 600
  601 LPPHKKKKSV LKSPLVALKN ALLKSTRPLR RMNSMVEPER KPKGLRRQQS MLERGVQRPY 660
  661 YPDEYPTYPA GFEERAHGGQ GMMQPHSQDA YYQRGGHYAP QQQEMMNSTY QNLEGEDIYG 720
  721 NIGNTVPRMP HHQDNGYGYD QYDLYANRAC IDLERRQAEA AAASGGRNGR RIVRRHSTTT 780
  781 ADRGGNPGPP RRPMISPGYE QDPQEIYQTR NGAYMLPDQR RAPSSEVMTR RRFYPGAANE 840
  841 QTEEEPLYQS RREMQREMQR NHLYQSKREM QERISQGKRD MEREFSPQSS SSQSEASNSE 900
  901 AIYQSRREAK ESALKTRSQL RDQIYQTRRE ALDSM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #7
Region A:
Residues: [1716-1878]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEPIYVSKRG MGRPAPIYET REESILQSRE NETDEKKEKE CKTEQIQVEI NAQPEEQIED  60
   61 STLSRSDLQK SSDTVIENPA RAPLVQDEVD DDEEEEVQDQ RDPAESSADQ TEQPTAIENN 120
  121 LHNEGMVEQS QNDSDDVFEA ADKVSPLAPP PAPVQPPTPR SGR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #8
Region A:
Residues: [1879-2090]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APFHISNILK RTAPPPSSPI GDSCTSIETQ YTSQASLPVG PPNATSTPFS SSMSLPIAGP  60
   61 VNNQPSANGR FPTLPREPST SRGFFDSNGG TLADKLWHVS LQIPPGAIPA GVRQEIYFTV 120
  121 SDPRMGQAVG GPPLDMENGE TMLSPLVMCG PQGLEFLVPV TLNIPHCAGR TASLGLALKA 180
  181 TDSEKNLHTE WDNIDLPSNA AAHTVSVKVD HF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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