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View Structure Prediction Details

Protein: dsx-PA, FBpp0303106
Organism: Drosophila melanogaster
Length: 549 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dsx-PA, FBpp0303106.

Description E-value Query
Range
Subject
Range
dsx-PB, FBpp0308... - The gene doublesex is referred to in FlyBase by the symbol Dmel\dsx (CG11094, FBgn0000504). It is a ...
215.0 [0..1] [423..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSEENWNSD TMSDSDMIDS KNDVCGGASS SSGSSISPRT PPNCARCRNH GLKITLKGHK  60
   61 RYCKFRYCTC EKCRLTADRQ RVMALQTALR RAQAQDEQRA LH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.09691
Match: 1lpvA
Description: DM domain of Doublesex (dsx)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [103-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHEVPPANPA ATTLLSHHHH VAAPAHVHAH HVHAHHAHGG HHSHHGHVLH HQQAAAAAAA  60
   61 APSAPASHLG GSSTAASSIH GHAHAHHVHM AAAAAASVAQ HQHQSHPHSH HHHHQNHHQH 120
  121 PHQQPATQTA LRSPPHSDHG GSVGPATSSS GGGAPSSSNA AAATSSNGSS GGGGGGGGGS 180
  181 SGGGAGGGRS SGTSVITSAD HHMTTVPTPA QSLEGSCDSS SPSPSSTSGA AILPISVSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [342-420]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRKNGANVPL GQDVFLDYCQ KLLEKFRYPW ELMPLMYVIL KDADANIEEA SRRIEEARVE  60
   61 INRTVAQIYY NYYTPMALV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.97
Match: 1zv1A
Description: Crystal structure of the dimerization domain of doublesex protein from D. melanogaster
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [421-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGAPMYLTYP SIEQGRYGAH FTHLPLTQIC PPTPEPLALS RSPSSPSGPS AVHNQKPSRP  60
   61 GSSNGTVHSA ASPTMVTTMA TTSSTPTLSR RQRSRSATPT TPPPPPPAHS SSNGAYHHGH 120
  121 HLVSSTAAT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle