YRC Public Data Repository - Protein Structure Prediction

Protein:	Spase18-21-PA
Organism:	Drosophila melanogaster
Length:	185 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Spase18-21-PA.

Description	E-value	Query Range	Subject Range
gi\|114658678 - gi\|114658678\|ref\|XP_510560.2\| PREDICTED: similar to SPC18 protein [Pan troglodytes]	238.0	[0..11]	[171..183]
gi\|54638969\|gb\|E... - GA15357-PA [Drosophila pseudoobscura], GA15357 [Drosophila pseudoobscura pseudoobscura] gi\|194112038, gi... - gi\|195152113\|ref\|XP_002016981.1\| GL21767 [Drosophila persimilis], gi\|194112038\|gb\|EDW34081.1\| GL2176... gi\|54638969, gi\|... - gi\|54638969\|gb\|EAL28371.1\| GA15357 [Drosophila pseudoobscura pseudoobscura], gi\|125776277\|ref\|XP_001...	234.0	[0..1]	[185..1]
gi\|66804101 - gi\|66804101\|gb\|AAY56665.1\| unknown [Drosophila melanogaster] gi\|66804111 - gi\|66804111\|gb\|AAY56666.1\| unknown [Drosophila simulans]	233.0	[0..1]	[185..1]
gi\|34784421 - gi\|34784421\|gb\|AAH57885.1\| Sec11a protein [Mus musculus]	232.0	[0..11]	[171..101]
gi\|109082238 - gi\|109082238\|ref\|XP_001084602.1\| PREDICTED: similar to Microsomal signal peptidase 18 kDa subunit (S...	229.0	[0..11]	[171..131]
gi\|86438376, gi\|... - gi\|86438376\|gb\|AAI12784.1\| SEC11 homolog C (S. cerevisiae) [Bos taurus], gi\|115496204\|ref\|NP_0010686...	227.0	[0..11]	[185..17]
gi\|194214714 - gi\|194214714\|ref\|XP_001489335.2\| PREDICTED: similar to Signal peptidase complex catalytic subunit SE... tr\|M3W609\|M3W609... - Signal peptidase complex catalytic subunit SEC11 OS=Felis catus GN=SEC11C PE=3 SV=1 SC11C_CANLF - Signal peptidase complex catalytic subunit SEC11C OS=Canis lupus familiaris GN=SEC11C PE=1 SV=3	227.0	[0..11]	[185..17]
SEC11C - SEC11 homolog C (S. cerevisiae) SC11C_PONAB - Signal peptidase complex catalytic subunit SEC11C OS=Pongo abelii GN=SEC11C PE=2 SV=3 SC11C_PONPY, SPC... - Microsomal signal peptidase 21 kDa subunit (EC 3.4.-.-) (SPase 21 kDa subunit) (SPC21) (SEC11-like 3...	227.0	[0..11]	[185..17]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVASMLQID EMLGDFNRMN KRQSLYQVLS FAMIVSSALM IWKGLMVVTG SESPIVVVLS  60
   61 GSMEPAFHRG DLLFLTNYKE EPVRVGEIVV FKVEGRDIPI VHRVIKLHEK EDGSVKFLTK 120
  121 GDNNNVDDRG LYAPNQLWLT KKDIVGRARG FLPYVGIITI FMNEYPKVKW AILSILAIFV 180
  181 LLHRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.154902
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits