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View Structure Prediction Details

Protein: FBpp0292799, FBp...
Organism: Drosophila melanogaster
Length: 1848 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0292799, FBp....

Description E-value Query
Range		 Subject
Range
gi|24644615, gi|... - gi|24644615|ref|NP_731085.1| grappa CG10272-PC, isoform C [Drosophila melanogaster], gi|23170668|gb|...
 628.0 [0..1] [1563..1]

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Predicted Domain #1
Region A:
Residues: [1-427] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPQVKDLV LRSPAGSSDV ISFAWPLQIG HGQDKHDNGI DIIDTIKFVC DELPSMSSAF  60
   61 EETNLHQIDT ACYKTMTGLV DRFNKAVDSI VALEKGTSLP AERLNKFAHP SLLRHILQLV 120
  121 YNAAVLDPDK LNQYEPFSPE VYGETSYELV QQMLKHVTVS KEDTFIDLGS GVGQVVLQMA 180
  181 GSFPLKTCIG IEKADTPARY AERMDVIFRQ YMGWFGKRFC EYKLIKGDFL VDEHRENITS 240
  241 STLVFVNNFA FGPTVDHQLK ERFADLRDGA RVVSSKSFCP LNFRITDRNL SDIGTIMHVS 300
  301 EIPPLKGSVS WTCKPVSYYL HVIDRTILER YFQRLKTKGG NDHESVGTVR TTRDRAKREA 360
  361 NVGQHHHNNH HSNNHANSNN HQRDREQSNG ATATAAHQQR HQSQSPANVS GAGIVLAASG 420
  421 QQAASKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 170.0
Match: 1nw3A
Description: Catalytic, N-terminal domain of histone methyltransferase Dot1l
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.723277178398499 bayes_pls_golite062009
transferase activity 0.64512166557639 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.54403439349476 bayes_pls_golite062009
methyltransferase activity 0.54389223881989 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [428-677] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQQLQHQHNQ QQRSLDMESS TESDGDATNG NGGNTTTATN TTSASNGPMT RKVWSDWCSS  60
   61 KGKSSQSDDE ENNNSNSNGG SNGGSIGGGS VGRQARATTQ KKRKKLTRKA AIASKSAAAA 120
  121 QREAEAAAAA AVSVPSKESS SKEDPPRAAS AGPGRKGRMK KGARGRKSLK IVGLEALHKQ 180
  181 TVLSTSLDTM TKKLPAAPGT VDQQLTALLT ENMSHAELDI PTAPQDTPYA LQILLDVFRS 240
  241 QYTSMIEHMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [678-767] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAYVPQVQK QIAQEQERMA RLKNRASQLD KQIKVLIDDS VALLKVRMNE LGIHVNSPND  60
   61 LIAQAKEIVG RHKDLQHTAS RMRNEVTFYE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #4
Region A:
Residues: [768-1704] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEQKLLLNKQ LKNLPEYQKL CGTVNGKVKL EVPPELSETT AQELVLKEIA NTLSQRKKLY  60
   61 AQVSTIEQET SVLQKTAEER STAATLLAQG TNMIVSTGSS SSSSTTVCAS AVTAQSNKLN 120
  121 SVKNSRRNRE HRARSQEWPE VPEVGKIQES NPEVLAQKIV ETCRQIEAGK FQGAGAPSSQ 180
  181 VNGKNKAIIE VPPPPATAPV SIKSSPGHHY KDTTLMPAPK QQQQQQMTLS QLPKCELPGL 240
  241 STSRKQESPK VANFEDRLKS IITTALNEDQ EQRSKAVESS PSPSPLHSPA PKRSKQHPAG 300
  301 AINPAQSLPN NLHNIITVST QGLMHLNANT TISPITPPLP GPGAGATAST APPPPANLPY 360
  361 GAYGGAVAKT TISGKYQAAK EPKYSPVRQA PLPPPPSHMA SLYPAGQQTT PADLGYQRRR 420
  421 SSVSATSYEH YMVQQQQQLQ QQQLMLAAAA HAAQRQQMRV EEQQQQQQHQ HHHHHHHHHP 480
  481 QHRLPQHVQH QHPHQHHPNE FKAPPADSHL QRSSSREQLI VEPPQTQPLE LLPRASSANS 540
  541 DYSGYRIRPP SRPSSNSSQP DYTQVSPAKM ALRRHLSQEK LSQHVTPQAT PPLPGHGGAP 600
  601 TSGKTIGDLV NGEIERTLEI SHQSIINAAV NMSTSGASFM ERAFLNERSN DRLLINLNAQ 660
  661 RPERVHVRPL SEESQDPQPT SYAQERGPGL GAGGAAAGGN SNLATLAHVA YAQKAQGGAR 720
  721 ANAGTAPPAT HSSSARSGRD YQPVALPRAE LKGSIEAYFH EEQQQKQSKG AGSAGSSSLR 780
  781 GPRLNGANPP LEGLAASLQD HVRARKYKEE TEERQRRAAA AASSSAGPPA GMELPTHYAH 840
  841 QAPPAHSYHH HGASINGTPH KVELGIKRSS PLAPHQQPPR PSKLAHYEPP TTQQQHAHAH 900
  901 LYANGQVLPP PPAHDATTPS PTPSSSSSSC GRRSNSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1y0fA
Description: No description for 1y0fA was found.

Predicted Domain #5
Region A:
Residues: [1705-1848] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGKLLVDPPL LMSPEINSLL GDERPLQLSH HQQQQQQMLH HHQSQQQQHL QLTQQQLRVA  60
   61 HLGHGLSHGH STMPTLGGQR NGNGNAADDV NDLATQRTIT NYDPRRRLRT TLSGPTKLSA 120
  121 AHSNQNLNGY VMADSSSSCP TIPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1y0fB
Description: No description for 1y0fB was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle