YRC Public Data Repository - Protein Structure Prediction

Protein:	CG5665-PA
Organism:	Drosophila melanogaster
Length:	291 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5665-PA.

Description	E-value	Query Range	Subject Range
gi\|67161 - gi\|67161\|pir\|\|LIPG triacylglycerol lipase (EC 3.1.1.3) - pig	249.0	[0..2]	[288..37]
LIPP_PIG - Pancreatic triacylglycerol lipase OS=Sus scrofa GN=PNLIP PE=1 SV=2	248.0	[0..2]	[288..38]
gi\|114632954 - gi\|114632954\|ref\|XP_001151144.1\| PREDICTED: pancreatic lipase [Pan troglodytes]	247.0	[0..2]	[288..54]
gi\|109090702 - gi\|109090702\|ref\|XP_001095070.1\| PREDICTED: similar to pancreatic lipase precursor [Macaca mulatta]	247.0	[0..2]	[288..54]
gi\|809239, gi\|80... - gi\|809239\|pdb\|1LPB\|B Chain B, The 2.46 Angstroms Resolution Structure Of The Pancreatic Lipase Colip...	246.0	[0..2]	[288..38]
gi\|157831229, gi... - gi\|1942400\|pdb\|1GPL\| Chain , Rp2 Lipase, gi\|157831229\|pdb\|1GPL\|A Chain A, Rp2 Lipase	246.0	[0..2]	[288..38]
gi\|54642078, gi\|... - gi\|54642078\|gb\|EAL30827.1\| GA19044-PA [Drosophila pseudoobscura], gi\|125978583\|ref\|XP_001353324.1\| G...	243.0	[0..1]	[290..1]

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Predicted Domain #1

Region A:
Residues: [1-291]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFQYMTPCQ NYSVPLLEAS KLWKHSRFSK GRKVVILATG WTNTVNESSA ISMISKAFMC  60
   61 RGDVNFVIVD AADYVDTFYA WSALNTDLIG EHIGVGLTHL IELTPLRNIH LIGHSLGAHI 120
  121 MGTAGRTFKK LTGKLIPRIT GLDPAKPCFR REKILPGLTR GDAKLVDIIH TNIGILAKRG 180
  181 PLGDVDFYPG GAHPIQPGCL TIGCSHTRAV EYFAESAYPH QEKNFMGKKC ASWDELRKRD 240
  241 CSAGIVSPMG YRMNPQARGI YYVDVNGWPP YGRNSENTVD PRLKTCYLCR R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.0
Match:	1ethA
Description:	Pancreatic lipase, C-terminal domain; Pancreatic lipase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.866238607554457	bayes_pls_golite062009
hydrolase activity	0.52702612560045	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: