YRC Public Data Repository - Protein Structure Prediction

Protein:	CG10116-PA
Organism:	Drosophila melanogaster
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG10116-PA.

Description	E-value	Query Range	Subject Range
LIPP_PIG - Pancreatic triacylglycerol lipase OS=Sus scrofa GN=PNLIP PE=1 SV=2	304.0	[0..3]	[288..18]
LIPP_MOUSE - Pancreatic triacylglycerol lipase OS=Mus musculus GN=Pnlip PE=1 SV=1	303.0	[0..3]	[288..34]
LIPP_ICTTR - Pancreatic triacylglycerol lipase OS=Ictidomys tridecemlineatus GN=PNLIP PE=1 SV=2	302.0	[0..3]	[288..34]
gi\|109090702 - gi\|109090702\|ref\|XP_001095070.1\| PREDICTED: similar to pancreatic lipase precursor [Macaca mulatta]	302.0	[0..3]	[288..34]
gi\|114632954 - gi\|114632954\|ref\|XP_001151144.1\| PREDICTED: pancreatic lipase [Pan troglodytes]	302.0	[0..3]	[288..34]
LIPP_RAT - Pancreatic triacylglycerol lipase OS=Rattus norvegicus GN=Pnlip PE=1 SV=1	301.0	[0..3]	[288..34]
LIPR2_CAVPO - Pancreatic lipase-related protein 2 OS=Cavia porcellus GN=PNLIPRP2 PE=1 SV=1	301.0	[0..3]	[288..18]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTGVQLALF LTLTIAAVYG ETGFFLNTRR VQENAQPIEA EVEALVRSSF YAADPTVVTI  60
   61 PRWLGNISSP EIPAVVSARL QQQDSNIISV DLSEANDETE IIDSVASLVI VLHNQFDMPL 120
  121 DRILVVGFAE GAHLAGGVAA KVQQDLGRQL SQITALDPSS GAELDHKLSQ ADAEFVEVVH 180
  181 TNAGGEGTWE RLGHVDYYPN GGQTQPGCTT DSCSHERAFE LLAEMWSPEN DFVSARCGSV 240
  241 ETLSASSCRW STHKMGQKQE EEQPASGIYF LETRQSSPFS RGAYFISFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.69897
Match:	1ethA
Description:	Pancreatic lipase, C-terminal domain; Pancreatic lipase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.866238607554457	bayes_pls_golite062009
hydrolase activity	0.52702612560045	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: