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View Structure Prediction Details

Protein: Ilp4-PA
Organism: Drosophila melanogaster
Length: 134 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ilp4-PA.

Description E-value Query
Range
Subject
Range
gi|13991923 - gi|13991923|gb|AAK51558.1|AF373021_1 preproinsulin [Catla catla]
110.0 [0..1] [133..1]
INS_ORENI - Insulin OS=Oreochromis niloticus GN=ins PE=1 SV=2
110.0 [0..2] [133..3]
gi|13517219 - gi|13517219|gb|AAK28709.1| preproinsulin [Catostomus commersoni]
109.0 [0..1] [133..1]
INS_CYPCA - Insulin OS=Cyprinus carpio GN=ins PE=1 SV=1
109.0 [0..1] [133..1]
INS_VERMO - Insulin OS=Verasper moseri GN=ins PE=3 SV=1
107.0 [0..2] [133..3]
INS_LOPPI - (P01341) Insulin precursor
INS_LOPAM - Insulin OS=Lophius americanus GN=ins PE=3 SV=1
106.0 [0..2] [133..3]
INS1_RAT - Insulin-1 OS=Rattus norvegicus GN=Ins1 PE=1 SV=1
106.0 [0..1] [133..1]
INS_MACFA - Insulin OS=Macaca fascicularis GN=INS PE=3 SV=1
104.0 [0..1] [133..1]
INS_CRILO - Insulin OS=Cricetulus longicaudatus GN=INS PE=1 SV=2
gi|305360, gi|21... - gi|305360|gb|AAA37089.1| preproinsulin, gi|2137094|pir||I48166 insulin precursor - golden hamster
104.0 [0..1] [133..1]
INS_CHLAE - Insulin OS=Chlorocebus aethiops GN=INS PE=1 SV=1
104.0 [0..1] [133..1]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLIRLGLAL LLLLATVSQL LQPVQGRRKM CGEALIQALD VICVNGFTRR VRRSSASKDA  60
   61 RVRDLIRKLQ QPDEDIEQET ETGRLKQKHT DADTEKGVPP AVGSGRKLRR HRRRIAHECC 120
  121 KEGCTYDDIL DYCA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1efeA
Description: Insulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.278956919805523 bayes_pls_golite062009
protein binding 0.06220495723124 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle