YRC Public Data Repository - Protein Structure Prediction

Protein:	se-PA
Organism:	Drosophila melanogaster
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for se-PA.

Description	E-value	Query Range	Subject Range
gi\|125979571, gi... - gi\|54640802\|gb\|EAL29553.1\| GA19859 [Drosophila pseudoobscura pseudoobscura], gi\|125979571\|ref\|XP_001... gi\|125979571\|ref... - GA19859-PA [Drosophila pseudoobscura], GA19859 [Drosophila pseudoobscura pseudoobscura]	183.0	[0..1]	[243..1]
gi\|50540310, gi\|... - gi\|50540310\|ref\|NP_001002621.1\| hypothetical protein LOC436894 [Danio rerio], gi\|49904398\|gb\|AAH7596...	182.0	[0..3]	[237..4]
CG6776-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6776 (CG6776, FBgn0035904). It is a protein...	177.0	[0..1]	[239..1]
gi\|46518247 - gi\|46518247\|emb\|CAD89618.1\| omega class glutathione S-transferase [Crassostrea gigas]	170.0	[0..1]	[243..1]
gi\|47222286 - gi\|47222286\|emb\|CAG05035.1\| unnamed protein product [Tetraodon nigroviridis]	169.0	[0..1]	[237..1]
gi\|11385535 - gi\|11385535\|gb\|AAG34850.1\|AF244707_1 glutathione S-transferase GST 42 [Zea mays]	167.0	[0..16]	[231..1]
gi\|15808378 - gi\|15808378\|gb\|AAL08414.1\| omega class glutathione-S-transferase [Takifugu rubripes]	166.0	[0..1]	[237..1]
gi\|114632703 - gi\|114632703\|ref\|XP_508020.2\| PREDICTED: hypothetical protein [Pan troglodytes]	166.0	[0..1]	[234..77]
GSTO1 - glutathione S-transferase omega 1	166.0	[0..1]	[234..1]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNGRHLAKG SPMPDVPEDG ILRLYSMRFC PFAQRVHLVL DAKQIPYHSI YINLTDKPEW  60
   61 LLEKNPQGKV PALEIVREPG PPVLTESLLI CEYLDEQYPL RPLYPRDPLK KVQDKLLIER 120
  121 FRAVLGAFFK ASDGGDLEPF WSGLDIYERE LARRGTEFFG GEQTGILDYM IWPWCERLEL 180
  181 LKLQRGEDYN YDQSRFPQLT LWLERMKRDP AVMAFYMEAE VQAEFLRTRS LGRPNYNLLV 240
  241 KDA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.221849
Match:	1eemA
Description:	Class omega GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.26520127994042	bayes_pls_golite062009
peroxidase activity	2.96616905270619	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.96616905270619	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
glutathione peroxidase activity	1.84498211544043	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.66635539173786	bayes_pls_golite062009
disulfide oxidoreductase activity	1.14955061683324	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
maleylacetoacetate isomerase activity	0.426921894831614	bayes_pls_golite062009
binding	0.419658151482326	bayes_pls_golite062009
oxidoreductase activity	0.314980210547407	bayes_pls_golite062009
protein binding	0.034515546627104	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: