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View Structure Prediction Details

Protein: CG1275-PC
Organism: Drosophila melanogaster
Length: 254 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1275-PC.

Description E-value Query
Range
Subject
Range
gi|109492061 - gi|109492061|ref|XP_001081563.1| PREDICTED: similar to Cytochrome b561 (Cytochrome b-561) [Rattus no...
276.0 [0..10] [246..278]
gi|220955800, gi... - gi|220955800|gb|ACL90443.1| CG1275-PA [synthetic construct], gi|220946120|gb|ACL85603.1| CG1275-PA [...
CG1275-PA, CG1275-PB - This gene is referred to in FlyBase by the symbol Dmel\CG1275 (CG1275, FBgn0035321). It is a protein...
256.0 [0..6] [254..92]
gi|54641023, gi|... - gi|54641023|gb|EAL29774.1| GA11787-PA [Drosophila pseudoobscura], gi|125980009|ref|XP_001354037.1| G...
248.0 [0..5] [254..109]
CY561_MOUSE - Cytochrome b561 OS=Mus musculus GN=Cyb561 PE=1 SV=2
240.0 [0..11] [246..4]
CY561_PONPY - Cytochrome b561 - Pongo pygmaeus (Orangutan)
CY561_PONAB - Cytochrome b561 OS=Pongo abelii GN=CYB561 PE=2 SV=1
234.0 [0..11] [246..5]
gi|27597088, gi|... - ref|NP_001906.2| cytochrome b-561 [Homo sapiens], gi|12804235|gb|AAH02976.1| Cytochrome b-561 [Homo...
233.0 [0..11] [246..5]
gi|109116771 - gi|109116771|ref|XP_001116102.1| PREDICTED: similar to Cytochrome b561 (Cytochrome b-561) [Macaca mu...
233.0 [0..11] [246..5]
gi|73965357 - gi|73965357|ref|XP_853258.1| PREDICTED: similar to Cytochrome b561 (Cytochrome b-561) [Canis familia...
232.0 [0..8] [246..3]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFSLGSGKA NMDPALINFK VLYVLTQLCG LTMIVLVATW IGQHFGGLAG TSNPGVEFNW  60
   61 HPLFMTIGFI YLYGNSILIY RGFRT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRKKTLKLTH AGIHMGAFIL TVIALKTVFD SHNLANPPIP NMYSLHSWLG LSAVIVFSLQ  60
   61 YVAGFVAFLA PGLRENYRIA MMPLHIYFGL FGFVLAIASA LMGITEKAIF AIKTPAYSTL 120
  121 PPAGVLANVI GVMYVVFGAL VVYLATEPSY KRKPIPEDTA LLNSSSVNE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.6
Match: 1kqfC
Description: Formate dehydrogenase N, cytochrome (gamma) subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ion transmembrane transporter activity 0.89088306929437 bayes_pls_golite062009
cation transmembrane transporter activity 0.890158298449879 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.814112055419571 bayes_pls_golite062009
substrate-specific transporter activity 0.812206012699042 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.773137851186839 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.762114046778875 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.679179334119734 bayes_pls_golite062009
transporter activity 0.629864849462794 bayes_pls_golite062009
transmembrane transporter activity 0.622501423809131 bayes_pls_golite062009
catalytic activity 0.349353660965659 bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity 0.143276144501499 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 0.143276144501499 bayes_pls_golite062009
binding 0.0102629993652836 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle