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View Structure Prediction Details

Protein: Eps-15-PA
Organism: Drosophila melanogaster
Length: 1253 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Eps-15-PA.

Description E-value Query
Range
Subject
Range
gi|21483594, gi|... - gi|21483594|gb|AAM52772.1| SD09478p [Drosophila melanogaster], gi|17426899|emb|CAD13484.1| Eps-15 pr...
495.0 [0..1] [1253..1]

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Predicted Domain #1
Region A:
Residues: [1-229]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVDFARVCG KHIGVYEAYY KLIDPKGTGA IEAMTAAKFL KKSGLSDVVL SRIWDLSDPS  60
   61 GKGFLDKPGF FVALKLVSLS QAGQVASMAN IYLDIANPPK LGELPKTMPS RIQTVPVASG 120
  121 GVANGDWSIG VIDRLKYEQL FESLHPSNGM LPGNKVKGVL MDSKLPMSIL GTIWDLADQD 180
  181 KDGNLDMHEF VVAMHLVYQT LQKRTIPSVL PPELRKPGGA GPPPKPAMP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 2qptA
Description: No description for 2qptA was found.

Predicted Domain #2
Region A:
Residues: [230-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPAGAAMPR APSGEGFGDG GFVANFPKDI APPAAIPPLP VAVPPMTRIP PVGAVSSQPL  60
   61 IQTDPLIPIG APVMANADWV VTPADLKRFE EIFRQSDLDK DGLVSGLEVK DIFIKSGIPQ 120
  121 RSLADIWALC DTNQSGKLTV EQFALAMWFV ERKQRGVDPP HVLNANMVPP SMRATVAGVD 180
  181 LQPQEVKPTY SNPELEMISK EIEELARERR VLETEIAQKE ADVRIKNGEV RSLQSELDTL 240
  241 TATLKQLENQ RGEAQKRLDD LQAQVSHNTA VLANVSLDIS RTNEQVTKIR DQCHMQEVTI 300
  301 NEQEGELNAK RSELQKLKDE EASLQKEYDS NNRELSKLTN HLQATQLQIS SVRSMVTQLL 360
  361 ETQRQMTDAL LICRAAMENQ NAELVSEYQL KIEPDFDEAR KTLTKEVQLP KDDPFEENNS 420
  421 GAANQATNGF GSDPFSGQPV NKPAISTGFD DSFNMSSGFD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [690-765]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGFDAFGQSG AGSAFGQTQR DPFGSDAFAA NKSNAITPEP GKDDFGSDPF AALHAPTGQG  60
   61 QVLSPNAQKS GPPPRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [766-819]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPSPALPPK KSKVPPPRPA PPRAAQPTGG FGSGGGGGFA DFDDFDNKLH HIPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [820-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APSPSATALS PLPPTLPAPI PVVSGSSLLD SFTLFDDPGQ IHKQAASTPN PTPITVPTVH  60
   61 TLLQTSLSTP AAPSPALASL STSGSGSVAG AGADLPSSVT ITT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [923-1034]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APSLNNQHLS RSNTPLQNQR TADVKLETKA VVSVFDAFGE IGTRKAPTPS LITGPTDFKD  60
   61 DPFKDYRYED PFSIKDPFAE EGEEELSEGK GADHKRNFAE DFSSGDEIGS AA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1035-1253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTLSNIVNNN SIKPKAATPL NNDLLQQFDA FNLNSSPAPS HHSGTSYHSN SKPSHDSQTA  60
   61 LDAFADFDDF AATLATTGGS GAATTATTTG NTKLNNSFFD AFNDNFSVIQ SSSVPTGVVR 120
  121 PNDQRAKAFD AFNDNFEDQF KTSPNANFAK FDGFEAHNFS SDFGNASFGT TGKEKQNGQV 180
  181 DKKFQSKEPV KDKFAADYSK PESFDADLEE ALKRSVLDN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle