YRC Public Data Repository - Protein Structure Prediction

Protein:	usnp-PA
Organism:	Drosophila melanogaster
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for usnp-PA.

Description	E-value	Query Range	Subject Range
gi\|54635247\|gb\|E... - GA10816-PA [Drosophila pseudoobscura], GA10816 [Drosophila pseudoobscura pseudoobscura] gi\|125806583, gi... - gi\|54635247\|gb\|EAL24650.1\| GA10816 [Drosophila pseudoobscura pseudoobscura], gi\|125806583\|ref\|XP_001...	155.0	[0..1]	[284..1]
gi\|481203 - gi\|481203\|pir\|\|S38309 SNAP-25 protein - chicken	155.0	[0..57]	[263..1]
gi\|109099266 - gi\|109099266\|ref\|XP_001111568.1\| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]	150.0	[0..67]	[283..131]
gi\|73958357 - gi\|73958357\|ref\|XP_547038.2\| PREDICTED: similar to Syntaxin-1B2 (Syntaxin 1B) (P35B) [Canis familiar...	150.0	[0..43]	[283..18]
gi\|531458, gi\|74... - gi\|7447071\|pir\|\|G01485 syntaxin - human, gi\|531458\|gb\|AAA20940.1\| syntaxin [Homo sapiens]	148.0	[0..60]	[283..1]
gi\|39593308, gi\|... - gi\|39593308\|emb\|CAE64778.1\| Hypothetical protein CBG09569 [Caenorhabditis briggsae], gi\|187031738\|em... gi\|157763374 - gi\|157763374\|ref\|XP_001674029.1\| Hypothetical protein CBG09569 [Caenorhabditis briggsae AF16]	145.0	[0..51]	[284..22]
gi\|50841439 - gi\|50841439\|gb\|AAT84082.1\| synaptosomal-associated protein [Carassius auratus]	145.0	[0..94]	[283..1]
gi\|108874618, gi... - gi\|157121261\|ref\|XP_001659889.1\| syntaxin, putative [Aedes aegypti], gi\|108874618\|gb\|EAT38843.1\| syn...	144.0	[0..49]	[283..3]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHNYLQPVH DHFDDVDRFE DVDDDLFLQN KRTGAAKLPQ QRSTNPFEMD DDDEEEITSS  60
   61 PSVAAQRLAY AEKRRAIEQR TLDSTNKSLG LLYETQEVGK ATAVELAKQR EQLEKTSHQL 120
  121 DEISSTLRFS QRHLTGLKSV FGGLKNYLSG NRDQPPTATG SPTGSQSSQE ANSNINQGAC 180
  181 GGASPSAPLS PAERYDNHPV SQLRGDPSST YQPQRQAANP FQAQIDSNLE EMCSNLSVLK 240
  241 MLATDLGGEI ESQNELLDNM NYKIEDVDLK IHKQNKDMSK LLKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1dn1B
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNAP receptor activity	3.50393203740159	bayes_pls_golite062009
binding	2.13344290488739	bayes_pls_golite062009
SNARE binding	1.85060343142976	bayes_pls_golite062009
transporter activity	1.74189664015129	bayes_pls_golite062009
protein binding	1.51700626946713	bayes_pls_golite062009
substrate-specific transporter activity	1.2360389745429	bayes_pls_golite062009
transmembrane transporter activity	1.13101548288086	bayes_pls_golite062009
phosphatidic acid binding	0.889573999146091	bayes_pls_golite062009
protein transporter activity	0.81087535212264	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.398018181744571	bayes_pls_golite062009
extracellular ligand-gated ion channel activity	0.27873535382283	bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity	0.27873535382283	bayes_pls_golite062009
ion transmembrane transporter activity	0.0981818568206971	bayes_pls_golite062009
phospholipid binding	0.0172309833091902	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: