YRC Public Data Repository - Protein Structure Prediction

Protein:	CG4019-PD, CG401...
Organism:	Drosophila melanogaster
Length:	249 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4019-PD, CG401....

Description	E-value	Query Range	Subject Range
gi\|69111664 - gi\|69111664\|gb\|AAZ03394.1\| Aqp4-Luc fusion protein [Reporter vector pmuAqp4-Luc]	243.0	[0..7]	[247..11]
gi\|69111702 - gi\|69111702\|gb\|AAZ03395.1\| Aqp4-Luc fusion protein [Reporter vector praAqp4-Luc]	242.0	[0..7]	[247..11]
gi\|73961781 - gi\|73961781\|ref\|XP_855456.1\| PREDICTED: similar to Aquaporin 4 (WCH4) (Mercurial-insensitive water c...	231.0	[0..7]	[249..108]
gi\|115459788, gi... - gi\|50927737\|ref\|XP_473424.1\| OSJNBb0034G17.15 [Oryza sativa (japonica cultivar-group)], gi\|38605857\|...	227.0	[0..5]	[237..14]
gi\|18481673 - gi\|18481673\|gb\|AAL73511.1\|AF465730_1 aquaporin-4 [Coturnix coturnix]	223.0	[0..7]	[247..45]
gi\|255646628 - gi\|255646628\|gb\|ACU23788.1\| unknown [Glycine max] PIP27_MAIZE - Aquaporin PIP2-7 OS=Zea mays GN=PIP2-7 PE=2 SV=1	223.0	[0..2]	[238..32]
gi\|52345956, gi\|... - gi\|52345956\|ref\|NP_001004765.1\| aquaporin 4 [Gallus gallus], gi\|52138496\|dbj\|BAD46731.1\| aquaporin 4...	223.0	[0..7]	[247..45]
gi\|62546339 - gi\|62546339\|gb\|AAX86046.1\| PIP2,2 [Glycine max]	222.0	[0..2]	[238..32]
gi\|17025878 - gi\|17025878\|gb\|AAL32127.1\| aquaporin [Medicago truncatula]	222.0	[0..2]	[238..32]
gi\|104391599 - gi\|104391599\|gb\|ABB13430.2\| plasma membrane intrinsic protein [Olea europaea]	221.0	[0..2]	[238..33]

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Predicted Domain #1

Region A:
Residues: [1-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGSTLDKIS AFLGELIGTG ILVFLGCMGC VKTDLFPNNH LQIVLNFGFA VLIAIQCFGC  60
   61 VSGAHLNPAV TVAAYIYEMV TLRMAFAYFA AQMLGAFIGY GLLMVLLPSP TLTVGAGLCV 120
  121 TLPHTSVTTG QALGIEFVIT SILVIVCCGV WDPRNSKFHD SVGIRFGLAI ACLACAAGPF 180
  181 TGGSMNPARS FAPALWNKHF ESNWIYWLAP LSSSAITAYA YKVVFRREVV EAEITSNEKL 240
  241 RQLEDVQLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	2d57A
Description:	Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits