YRC Public Data Repository - Protein Structure Prediction

Protein:	cpa-PA
Organism:	Drosophila melanogaster
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cpa-PA.

Description	E-value	Query Range	Subject Range
CAZA1_RAT - F-actin-capping protein subunit alpha-1 OS=Rattus norvegicus GN=Capza1 PE=1 SV=1	481.0	[0..3]	[284..5]
CAZA1_BOVIN - F-actin-capping protein subunit alpha-1 OS=Bos taurus GN=CAPZA1 PE=2 SV=1	481.0	[0..3]	[284..5]
gi\|61371588, gi\|... - gi\|61371588\|gb\|AAX43695.1\| capping protein muscle Z-line alpha 1 [synthetic construct], gi\|61365542\|...	481.0	[0..6]	[284..8]
CAPZA1 - capping protein (actin filament) muscle Z-line, alpha 1 gi\|123979702, gi... - gi\|61355548\|gb\|AAX41151.1\| capping protein muscle Z-line alpha 1 [synthetic construct], gi\|60821852\|...	480.0	[0..6]	[284..8]
CAZA1_CHICK - F-actin-capping protein subunit alpha-1 OS=Gallus gallus GN=CAPZA1 PE=1 SV=1	480.0	[0..3]	[284..5]
gi\|109013601 - gi\|109013601\|ref\|XP_001107677.1\| PREDICTED: F-actin capping protein alpha-1 subunit [Macaca mulatta]	480.0	[0..6]	[284..8]
CAZA1_PONAB - F-actin-capping protein subunit alpha-1 OS=Pongo abelii GN=CAPZA1 PE=2 SV=3 CAZA1_PONPY - F-actin-capping protein subunit alpha-1 - Pongo pygmaeus (Orangutan)	478.0	[0..6]	[284..8]
gi\|73981496 - gi\|73981496\|ref\|XP_533066.2\| PREDICTED: similar to capping protein (actin filament) muscle Z-line, a...	478.0	[0..3]	[284..5]
gi\|38322729 - gi\|38322729\|gb\|AAR16282.1\| capping protein (actin filament) muscle Z-line, alpha 2 [Takifugu rubripe...	478.0	[0..3]	[284..5]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQTPITDAE KVRIVSDFIL HAPPGEFNEV FNDVRELLKN DTLLKDGASH AFAQYNKDQL  60
   61 TPVRIEGTDH NAIISEHNDL GNGRFYDPRT KQAFKYDHLR KEASDYQDVE ADATAEPWRA 120
  121 ALDLETLAYT ASHYRHGVSS VFGKAQGNQI TLTICIEDHQ FQPKNYWNGR WRSQWHVTFQ 180
  181 AGSGTAELKG VLKVQVHYYE DGNVQLVSSK ECRESVVVSN EQQVAKEVIR LIEDAENEYQ 240
  241 LAISENYQTM SDTTFKAMRR QLPITRTKID WSKIVSYSIG KELKTQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1iznA
Description:	Capz alpha-1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	6.56144513012007	bayes_pls_golite062009
actin filament binding	5.39928513902709	bayes_pls_golite062009
cytoskeletal protein binding	5.10504476256679	bayes_pls_golite062009
binding	2.03345990933192	bayes_pls_golite062009
protein binding	1.31870344025745	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: