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View Structure Prediction Details

Protein: CG10737-PS
Organism: Drosophila melanogaster
Length: 870 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG10737-PS.

Description E-value Query
Range
Subject
Range
CG10737-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10737 (CG10737, FBgn0034420). It is a prote...
544.0 [0..1] [858..1]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLADQIDDY ICSFEGLGDL TMDSLAIFIF LWAVLALFSV WLIKLLYHKY LNKDKSASAA  60
   61 NSRQTSVAPT SGSPTSVAGK TEKRLSEPRD LLATKSKVEG LDLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPLAGASGGR GRSSASPLNT AGAAAGGPRR RVVRQSSTGP ENRKKRYVPP PSNVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [160-358]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPETSSVTWT SQVFRWLYSD LVIVNELLMS WVIAINDTLR KSVEEHGVAV EVVRVLPDSP  60
   61 APGLNNIFCN CDENNPADML ITFDCDAMPV LQVKTFRQKS GKVETSHYKV TVSRFRARMA 120
  121 IPMNYNSLKG EMRVEGYPDV RIAMNSVGAI KAMDQDEQQL QTVISDILTT ALRDTIYPVD 180
  181 FSIYSTCPRA EVEPLDLPH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [359-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMEQHMGGVG LRDSQHMVSG RRLLVKIVKG DGIRDAQNPY VVIEMDEPAQ KNQTGTQRGG  60
   61 KPFWDEHFLF ELSPQSAEIL FEVYDHPVIA SDPPKFLGLG LVGIDELAVG PASTQLLQLQ 120
  121 PRPYETQPVS GAITVDFVFI EGAEIPAGAR PQRLKEALRL STPAINEHIR NGADLADAAV 180
  181 RALQDGALSS SGSGGQPSKS TLIIHSVQRN SSSPNAFKVE LNRDGQIEVT DTATELDQAV 240
  241 AQAFERAANE AQTELELELA KEEKSSQLGE PLIDSGNGTV NEESTAEFGQ PNAASSPNGS 300
  301 SYHNNYSLNG NGNSNGAGSG GYNSLPRNGG AQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 1dqvA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [692-792]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAQQSGLLEG HDVVDDRGRS KKRPRMGIGH SITDHSRRSS ISESSAISGF SSASNKTYVH  60
   61 EASTLVLETI ENGIKRHFIV PLAIAQRPRW RRKGTKLHIY N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [793-870]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHTFIAKHLS GSGLQCSICM KSIPRRPGKQ GYECRDCQLI SHKQCHIRAP QACPNPTVLS  60
   61 MELTKLNSAA ADRSIRKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.0980674097362609 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle