YRC Public Data Repository - Protein Structure Prediction

Protein:	CG5189-PB, CG5189-PA
Organism:	Drosophila melanogaster
Length:	125 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5189-PB, CG5189-PA.

Description	E-value	Query Range	Subject Range
LTR2B_XENLA - Ragulator complex protein LAMTOR2-B OS=Xenopus laevis GN=lamtor2-b PE=2 SV=1	209.0	[0..1]	[125..1]
gi\|39840980 - gi\|39840980\|gb\|AAR31126.1\| RE43922p [Drosophila melanogaster]	206.0	[0..1]	[125..1]
gi\|62738001 - gi\|62738001\|pdb\|1SZV\|A Chain A, Structure Of The Adaptor Protein P14 Reveals A Profilin- Like Fold W...	206.0	[0..1]	[125..6]
tr\|M3XCQ5\|M3XCQ5... - Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 OS=Felis catus GN=LAMTOR2 PE=4 SV=1 gi\|123999266 - gi\|123999266\|gb\|ABM87211.1\| mitogen-activated protein-binding protein-interacting protein [synthetic... gi\|114560209 - gi\|114560209\|ref\|XP_001163747.1\| PREDICTED: mitogen-activated protein-binding protein-interacting pr... tr\|G3HG98\|G3HG98... - Mitogen-activated protein-binding protein-interacting protein OS=Cricetulus griseus GN=I79_009619 PE... gi\|57089103 - gi\|57089103\|ref\|XP_537247.1\| PREDICTED: similar to Late endosomal/lysosomal Mp1 interacting protein ... LTOR2_BOVIN - Ragulator complex protein LAMTOR2 OS=Bos taurus GN=LAMTOR2 PE=2 SV=1 CCDS1128.1_1 - null ROBLD3 - roadblock domain containing 3 gi\|109017305, gi... - gi\|109017307\|ref\|XP_001116330.1\| PREDICTED: mitogen-activated protein-binding protein-interacting pr... gi\|149751581 - gi\|149751581\|ref\|XP_001499905.1\| PREDICTED: similar to Mitogen-activated protein-binding protein-int... gi\|194036025, gi... - gi\|194036029\|ref\|XP_001928483.1\| PREDICTED: similar to Mitogen-activated protein-binding protein-int...	205.0	[0..1]	[125..1]
LTOR2_DANRE - Ragulator complex protein LAMTOR2 OS=Danio rerio GN=lamtor2 PE=2 SV=1	202.0	[0..1]	[125..1]
LTOR2_XENTR - Ragulator complex protein LAMTOR2 OS=Xenopus tropicalis GN=lamtor2 PE=2 SV=1	202.0	[0..1]	[125..1]
gi\|21292242, gi\|... - gi\|31199249\|ref\|XP_308572.1\| AGAP007213-PA [Anopheles gambiae str. PEST], gi\|21292242\|gb\|EAA04387.1\|... AGAP007213-PA - Mitogen-activated protein-binding protein-interacting protein\|protein_coding\|2L:44367385:44367839:1\|...	200.0	[0..1]	[125..1]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKPKALTQV LSQANTGGVE NTLLLSQEGA LLAYSGYGDK DARITAAIAS NIWAAYEKHG  60
   61 RNAFREGRLT FVLIDCENGH VAITQVASVL LCLYAKQTVG LGLLKQKAMS LASYLERPLK 120
  121 QISAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.69897
Match:	1szvA
Description:	Structure of the Adaptor Protein p14 reveals a Profilin-like Fold with Novel Function
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.71666129389655	bayes_pls_golite062009
protein binding	0.938282161933492	bayes_pls_golite062009
catalytic activity	0.414641636618101	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: