YRC Public Data Repository - Protein Structure Prediction

Protein:	icln-PA
Organism:	Drosophila melanogaster
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for icln-PA.

Description	E-value	Query Range	Subject Range
gi\|6646935, gi\|1... - gi\|6646935\|gb\|AAF21126.1\|AF216522_1 ICLn protein [Drosophila melanogaster], gi\|19527675\|gb\|AAL89952....	275.0	[0..1]	[215..1]
gi\|38048091, gi\|... - gi\|38048091\|gb\|AAR09948.1\| similar to Drosophila melanogaster icln [Drosophila yakuba], gi\|195487831...	254.0	[0..1]	[215..1]
gi\|125809634, gi... - gi\|54636377\|gb\|EAL25780.1\| GA18528 [Drosophila pseudoobscura pseudoobscura], gi\|125809634\|ref\|XP_001... gi\|54636377\|gb\|E... - GA18528-PA [Drosophila pseudoobscura], GA18528 [Drosophila pseudoobscura pseudoobscura]	226.0	[0..1]	[215..1]
gi\|115481276, gi... - gi\|222612504\|gb\|EEE50636.1\| hypothetical protein OsJ_30846 [Oryza sativa Japonica Group], gi\|2157684... gi\|218184193 - gi\|218184193\|gb\|EEC66620.1\| hypothetical protein OsI_32859 [Oryza sativa Indica Group]	175.0	[0..8]	[215..21]
gi\|1770220 - gi\|1770220\|emb\|CAA69718.1\| swelling dependent chloride channel, ICln [Danio rerio]	165.0	[0..1]	[171..1]
gi\|71042566 - gi\|71042566\|pdb\|1ZYI\|A Chain A, Solution Structure Of Icln, A Multifunctional Protein Involved In Re...	162.0	[0..1]	[161..10]
gi\|19263324, gi\|... - gi\|74141910\|dbj\|BAE41022.1\| unnamed protein product [Mus musculus], gi\|26327689\|dbj\|BAC27588.1\| unna...	160.0	[0..1]	[161..6]
gi\|114639484 - gi\|114639484\|ref\|XP_001175048.1\| PREDICTED: chloride channel, nucleotide-sensitive, 1A isoform 1 [Pa...	160.0	[0..1]	[161..1]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLIMRVSPP EHGLLYTANN IKLKLGDKVV GEGTVYIAQN TLSWQPTELA EGISIEWKQV  60
   61 SLHGISSNPR KCIYFMLDHK VEWNGVYGDP PQQAVNGRNG GGSEAEVDEG NGSDEHDEDD 120
  121 NFEDAVDEQF GEVTECWLMP EDIHTVDTMY SAMTTCQALH PDSANSDSED SDPMQDAGGL 180
  181 EDEAMEEDDA LTLGRNGVQN LSLDDDEERF EDADE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.09691
Match:	1zyiA
Description:	Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and rna splicing
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits