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View Structure Prediction Details

Protein: FBpp0311789, CG4...
Organism: Drosophila melanogaster
Length: 289 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311789, CG4....

Description E-value Query
Range
Subject
Range
gi|114623942 - gi|114623942|ref|XP_001153022.1| PREDICTED: similar to Chain A, Structure Of Human 5-Deoxy-5-Methylt...
MTAP - methylthioadenosine phosphorylase
MTAP_MACMU - S-methyl-5'-thioadenosine phosphorylase OS=Macaca mulatta GN=MTAP PE=3 SV=1
CCDS6509.1_1 - null
309.0 [0..8] [285..2]
MTAP_MOUSE - S-methyl-5'-thioadenosine phosphorylase OS=Mus musculus GN=Mtap PE=1 SV=1
308.0 [0..14] [285..8]
gi|114623944 - gi|114623944|ref|XP_001152767.1| PREDICTED: similar to MTAP isoform 1 [Pan troglodytes]
306.0 [0..17] [285..28]
gi|73971706 - gi|73971706|ref|XP_531959.2| PREDICTED: similar to S-methyl-5-thioadenosine phosphorylase (5-methylt...
304.0 [0..18] [285..95]
MTAP_DANRE - S-methyl-5'-thioadenosine phosphorylase OS=Danio rerio GN=mtap PE=2 SV=2
297.0 [0..16] [285..7]

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Predicted Domain #1
Region A:
Residues: [1-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITIKCKDTN LDPLPVKIGI IGGSGLDDPD ILEQRQERVV ETPYGEPSDA LIEGEINGVQ  60
   61 CVLLARHGRK HDIMPSNVNY RANIWALRDV GCTHLIVSTA CGSLREEIKP GNLVVPHDFI 120
  121 DRTTKRLQTF YDGKAQSPRG VCHLPMFPAF SERTRNILLQ AAKELEIPAH DKATIVTIEG 180
  181 PRFSSRSESH MFRQWGGDLI NMTTCPEVVL AKEAGLLYGS VAIATDYDCW RMGCEGVNVQ 240
  241 DVLRTFAENV IKVKKILVNA VGRIAKEDWS EDILNAKQCV CNNTMSGAM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.09691
Match: 1cb0A
Description: 5'-deoxy-5'-methylthioadenosine phosphorylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-methyl-5-thioadenosine phosphorylase activity 3.89303327575747 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.66765825367784 bayes_pls_golite062009
purine-nucleoside phosphorylase activity 2.88401222133542 bayes_pls_golite062009
transferase activity 2.19158134892504 bayes_pls_golite062009
catalytic activity 2.18268586151113 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.01261001022129 bayes_pls_golite062009
protein binding 0.0400212181978007 bayes_pls_golite062009

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