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View Structure Prediction Details

Protein: cnk-PA, FBpp0309189
Organism: Drosophila melanogaster
Length: 1557 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cnk-PA, FBpp0309189.

Description E-value Query
Range
Subject
Range
gi|157134910, gi... - gi|157134910|ref|XP_001663353.1| hypothetical protein AaeL_AAEL013175 [Aedes aegypti], gi|108870371|...
463.0 [0..641] [1514..134]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYINIAEWT PDQVTDWIKG LDESMKGYLY EFSKQEIGGR ALLNIRPYEL ENLGMLRIGH  60
   61 QEIVLEAVEN LRNFHYHLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 2eanA
Description: No description for 2eanA was found.

Predicted Domain #2
Region A:
Residues: [80-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDNLQFMALH VATAAKNLHR ELARNHAEST KIDTRILHDI TRTIATLKPL VGSLERTPFR  60
   61 KQEMYREYCG NVLKCGLELA TIAHR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.30103
Match: 1p1dA
Description: Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [165-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRFALQPVPA IRQSAERLEN LANFVIQDIS DPMVLQPASL NLVTLKKRES ELGFNIESSY  60
   61 NGIHRVTDIK YNSPAHNSGK IEDGDEIVQI NYQTVVGWQH RTVLEHLREA LPDVVLTVKK 120
  121 RPKHTKMFGQ IYMQPYRLPS KKRNMAARWA AQMPSPRAAF LTLDTEQLAT GGTGSAVPDP 180
  181 SKSLSSEKRE VLTKANPVSS ASDSDSSCSD IPTPTDPKLA A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1z87A
Description: solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [386-614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REIRLYYPKP RALLQRRNTI CGCEYLSLKN SDLVVPSWHE RKPGIGSPTN CDPGSPSIRD  60
   61 KSISFGYGLE MAARPTTCIG IAGDTSTDKA RRMFHEARKL KQLTEDSQRE FLVDRYKPGV 120
  121 SKVVRFDAKE DYVMKNEKFI CNVENTILET FEPIPFADEG DEDALETLRN CKTENAEELL 180
  181 EAINLATKGQ DLPLAEAINM PLLQQGRRGR LDKSHSTPAY DNSGEESDT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [615-710]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPAIEPRKEF LLVTPPAPPP RPRKQREMTP PAVPPPPPKP ASMQPASSIT SISIPVPVPV  60
   61 PAAVDPSEIS ELHTPSKSRT LTLKKKHSLM AKRRNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [711-885]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLKLLGTGDI QGHLYRRKKN HRGVTYWARI YFVMLDTILY GFRSKQSTSA SLVIFLPGFT  60
   61 VSLAKEVHSK PHAFKVYHTA KSFYFAAESL DALNQWVDFL RQASLKVPPS TGSKGGGDAK 120
  121 DLYSENDSSG EECDALVIQN LSTPSPQGNK ESMSMSMTLS GGTPPSSAPI KHERG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 2j59M
Description: No description for 2j59M was found.

Predicted Domain #7
Region A:
Residues: [886-1034]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLDSFRKFTN TFKSSAAKPS SDIPVPTEQY RSYRKVPGGS FGIQIGANTP GYHDPAMPPT  60
   61 QIPPLVGPKL SRSSSRSSVV SGTESAVSLS ASILGPPASP APTPTPTATP TSLQHQSSEE 120
  121 SPSQSQSQSP SSKSSLKKAP FNFLHASNP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1035-1153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLVEFDFHTS KTLLPKMSVG NTLDHGHNIQ GFVTLKDLML RKQEEEAQEM YNNRVHLGVE  60
   61 KHKHARTEST ASQQSAMSSS VTKPLEKLPK IQSVSLPKTP DYEISFKPDD ESIKRTRTK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1154-1387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGQKLRDFGY ELICGDEPST SSISRQEHHH HHHHHQHHLQ HVQQQQQLQH QQTQQQHSSK  60
   61 AKHFLRSQQL QLSSFLHKNS SGGSGKSSGS GADQKKSKGK SSGDRRFPFS KHSTGSAGSG 120
  121 CGPGHAMTMT LPLNKKSKSN HALDGAVGNG VTIIGSGSSI KKSQTYNQDL RDKIVGTKYD 180
  181 AHRKNSAPIP IFSKLSISGG TPAKPSKENR FLGSPLLHRT LFGHHHHQQQ AVTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1388-1447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSADPDCDQ EIFSQITLPT HNQAGYRSYR GPGILTTSTT NLCSSEGLQP PLPPAPPPPV  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1448-1557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTSRQREEEQ AEATISECAA TPKVSSSGSV DSKAATPDYP NMECPPVFEP EIYSLSDTSL  60
   61 SRIVMRTPSS SGATSATAST TTTNNNNNNN NTNNNTNTNS SPSGGEHHQT 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle