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View Structure Prediction Details

Protein: gi|7303418, gi|2...
Organism: Drosophila melanogaster
Length: 542 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7303418, gi|2....

Description E-value Query
Range
Subject
Range
CG8646-PB - This gene is referred to in FlyBase by the symbol Dmel\CG8646 (CG8646, FBgn0033763). It is a protein...
419.0 [0..1] [542..1]

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Predicted Domain #1
Region A:
Residues: [1-542]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWFLWLICLL LPIIDAAEVE KSPAKPNIIF ILADDLGFND VGFHGSAEIP TPNIDALAYS  60
   61 GIILNRYYVA PICTPSRSAL MTGKYPIHTG MQHTVLYAAE PRGLPLEEKI LPQYLNELGY 120
  121 TSHIAGKWHL GHWKLKYTPL YRGFSSHWGL DMRNGTQVAY DLHGHYTTDV ITDHSVKVIA 180
  181 NHNATKGPLF LYVAHAACHS SNPYNPLPVP DNDVIKMSHI PNYKRRKFAA MVSKMDNSVG 240
  241 QIVDQLRKSN MLENSIIIFS SDNGGPAQGF NLNFASNYPL KGVKNTLWEG GVRAAGLMWS 300
  301 PLLKKSQRVS NQTMHIIDWL PTLLEAAGGQ PALSNLSKQI DGQSIWRALV QDKASPRLNV 360
  361 LHNIDDIWGS AALSVGDWKL VKGTNYRGSW DGWYGPAGER DPRLYDWQLV GRSRAGKALE 420
  421 ALKMLPSRAD QQRIRAAATV SCPGQSSQGT SCVATAFSAP CLFHIRDDPC EQYNLAKQYP 480
  481 EVVNALMTEL ERFNATAVPP SNKPADPRAD PRFWNYTWTN FGDYQNNDLD TFSGDITLAK 540
  541 TV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.30103
Match: 1fsuA
Description: 4-SULFATASE (HUMAN)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sulfuric ester hydrolase activity 5.36665355899045 bayes_pls_golite062009
hydrolase activity 4.01787687283658 bayes_pls_golite062009
arylsulfatase activity 3.11969928063277 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.33954471377666 bayes_pls_golite062009
catalytic activity 2.31328968099128 bayes_pls_golite062009
steryl-sulfatase activity 1.90163490875396 bayes_pls_golite062009
binding 0.699784512591091 bayes_pls_golite062009
protein binding 0.208332656410563 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle