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View Structure Prediction Details

Protein: Sin3A-PA, FBpp02...
Organism: Drosophila melanogaster
Length: 1776 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sin3A-PA, FBpp02....

Description E-value Query
Range
Subject
Range
gi|2570794 - gi|2570794|gb|AAB82273.1| transcriptional co-repressor SIN3A [Drosophila melanogaster]
1293.0 [0..1] [1776..1]

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Predicted Domain #1
Region A:
Residues: [1-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRTRVDEV QFGTRPVPQT SGGVGVGVVG VTGGGPTSGG GGTATVGVNT TGVTIGTVVP  60
   61 SAHNATISGI GSIHHRILTP QHGGAQTIAY LPSTTPTATN LKTTTSIVDS TTAGGPVGAG 120
  121 AQVAVGVGSA AGGGGVVVST GSTGTQTLQY TTSYSVASIQ AGGTLKANTA DGANTVQIHV 180
  181 TGGGAANNPA SAQTVSSSSQ TGTIRQRTIS GTQTVATAVG NLATISQQQP VQQSPLGKAQ 240
  241 TPPSSVVANS IPVGGTTPPQ GQSGNATPRL KVEDALSYLD QVKYQYADQP QIYNNFLDIM 300
  301 KEFKSHCIDT PGVIERVSTL FKGHTELIYG FNMFLPPGYK IEIHSDALGC SVPVVSMPSP 360
  361 PGAPTSTGTV HMLTGNSSMS GAGHIAIKTT NAATLTPAAG AGAAAAAAAV AQIQSAGAVN 420
  421 LMTHGGASLT QTTIHALQQA TPPQSQSPGG GHVHVSVTNS TAANAVVPGQ PGISVSAHNV 480
  481 PQNYSRDRER ATITPTGQVA GAAANVNASA SIVVGGPPTP NSLSELSPHG GAGGGPGAGA 540
  541 AQHNLHHIQQ AHQSILLGET GQQNQPVEFN HAITYVNKIK NRFQNQPAKY KKFLEILHDY 600
  601 QREQKVMKEG SLNQGKMLTE QEVYTQVAKL FGQDEDLLRE FGQFLPDATN HQSGQYMSKS 660
  661 ASVHNDHGKR PTATLSGGAH ITMSSASPAP SGSPLHLGAT TLPQIDKSAH AAAIGNLSAV 720
  721 NTSVSIKTYN NNQQQQNHVI GSGLNATRND ILFEKDYHAG LQQQAHQRGA GVGGHHHLAG 780
  781 TAAGANIGRP GVGASVMVSY DKEHRNNHHV QKYVGHAPNQ NLTHGHNAKK SPSYGIPSVI 840
  841 GSMPHISDNS LDRSSPGISY ATPPLPSGPH GQHNSGSATR RPGDDSLVGH YASGAPPAKR 900
  901 PKPYCRDVSF SEASSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [917-987]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CTISDAAFFD KVRKALRSPE VYDNFLRCLT LFNQEIVSKT ELLGLVSPFL MKFPDLLRWF  60
   61 TDFLGPPSGQ P

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.11
Match: 2cr7A
Description: Solution structure of the first PAH domain of the mouse transcriptional repressor SIN3B
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [988-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGLIDGMPL AATQRQGGGS SNSSHDRGTS HQSAAEYVQD VDLSSCKRLG ASYCALPQST  60
   61 VPKKCSGRTA LCREVLNDKW VSFPTWASED STFVTSRKTQ FEETIYRTED ERFELDLVIE 120
  121 VNSATIRVLE NLQKKMSRMS TEELSKFHLD DHLGG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 64.376751
Match: PF08295.3
Description: No description for PF08295.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1143-1366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQTIHQRAI HRIYGDKSGE IITGMKKNPF VAVPIVLKRL KVKEEEWREA QKTFNKQWRE  60
   61 QNEKYYLKSL DHQAINFKPN DMKALRSKSL FNEIETLYDE RHDQEDDAME PFGPHLVLPY 120
  121 KDKTILDDAA NLLIHHVKRQ TGIQKQEKQK IKQIIRQFVP DLFFAPRQPL SDDERDDAFP 180
  181 FLVDDNTKMD VDSPLGRTES STRNAKSTPS ESASPARSNA STSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1367-1491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTPAGIKKET DDSKATTGSF APASSATASS ATPVDDATPS TSSAAAAASA ASSSTVSGTE  60
   61 GKPKDDPLSS HKEEGAGSTS SGVATSPRQA QDTAGAGVDV EIKLEHPADF SNPKLLPPHA 120
  121 HGQRE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1492-1776]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DESYTLFFAN NNWYLFLRLH AILCDRLHVM YERARLLAIE EERCRVNRRE STATALRLKP  60
   61 KPEIQVEDYY PTFLDMLKNV LDGNMDSNTF EDTMREMFGI YAYISFTLDK VVSNAVRQLQ 120
  121 YCVTERAALD CVELFATEQR RGCTGGFCRD AHKTFDREMS YQRKAESILN EENCFKVYIY 180
  181 KIDCRVTIEL LDSEPEEVDK PAALKAQKFS KYVERLANPA LGGGGNTGRS DSALGNDSVV 240
  241 DGSDIKTEAD EDTAEHTQSQ QWTLLESENE KYIWSSPLKI HVQSY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle