YRC Public Data Repository - Protein Structure Prediction

Protein:	CG7777-PA
Organism:	Drosophila melanogaster
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7777-PA.

Description	E-value	Query Range	Subject Range
gi\|69111664 - gi\|69111664\|gb\|AAZ03394.1\| Aqp4-Luc fusion protein [Reporter vector pmuAqp4-Luc]	243.0	[0..19]	[252..11]
gi\|69111702 - gi\|69111702\|gb\|AAZ03395.1\| Aqp4-Luc fusion protein [Reporter vector praAqp4-Luc]	241.0	[0..19]	[252..11]
gi\|125807882, gi... - gi\|54635720\|gb\|EAL25123.1\| GA20580-PA [Drosophila pseudoobscura], gi\|125807882\|ref\|XP_001360548.1\| G...	235.0	[0..1]	[255..1]
gi\|73961781 - gi\|73961781\|ref\|XP_855456.1\| PREDICTED: similar to Aquaporin 4 (WCH4) (Mercurial-insensitive water c...	231.0	[0..19]	[255..108]
CG7777-PB - This gene is referred to in FlyBase by the symbol Dmel\CG7777 (CG7777, FBgn0033635). It is a protein... gi\|220955652, gi... - gi\|220955652\|gb\|ACL90369.1\| CG7777-PB [synthetic construct], gi\|220945890\|gb\|ACL85488.1\| CG7777-PB [...	228.0	[0..1]	[255..1]
gi\|148669653, gi... - gi\|18481727\|gb\|AAL73545.1\|AF469168_1 aquaporin-4 M1 isoform [Mus musculus], gi\|160415211\|ref\|NP_0338...	224.0	[0..19]	[252..33]
gi\|114612688 - gi\|114612688\|ref\|XP_001166359.1\| PREDICTED: aquaporin 1 isoform 2 [Pan troglodytes]	224.0	[0..14]	[259..4]
AQP4_DIPME - Aquaporin-4 OS=Dipodomys merriami GN=AQP4 PE=2 SV=1	224.0	[0..19]	[252..33]
gi\|2135623, gi\|1... - pir\|\|I39178 aquaporin 4, long splice form - human, gi\|1072055\|gb\|AAC52112.1\| mercurial-insensitive w...	223.0	[0..19]	[252..51]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKFEYSLGL NELKSKELRL WQALIGEFLG NLILNFFACG ACTQIEDGTF KALAFGLAIF  60
   61 MAITIVGHLS GGHVNPAVTA GMLVAGRISL IRAFFYVVFQ CLGAIAGTAA VKILIDQDYY 120
  121 NGLGHTSLAP NITELQGLGI EFFLGLLLVL VVFGACDPHK PDSRYTAPLA IGMAVTLGHL 180
  181 GTIRYTGASM NPARTVGTAF ATDIWASHWV YWVGPVLGGV AAALLYTQVL EAKPVPKVNE 240
  241 ASEKYRTHAD EREMRKLEGA RDYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.39794
Match:	2d57A
Description:	Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits