YRC Public Data Repository - Protein Structure Prediction

Protein:	sPLA2-PA, sPLA2-PC
Organism:	Drosophila melanogaster
Length:	186 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sPLA2-PA, sPLA2-PC.

Description	E-value	Query Range	Subject Range
gi\|51091995 - gi\|51091995\|gb\|AAT94411.1\| RH74002p [Drosophila melanogaster]	315.0	[0..1]	[186..1]
gi\|125806977, gi... - gi\|54635385\|gb\|EAL24788.1\| GA10773-PA [Drosophila pseudoobscura], gi\|125806977\|ref\|XP_001360214.1\| G...	269.0	[0..1]	[181..1]
PA2_APIME - Phospholipase A2 OS=Apis mellifera PE=1 SV=3	211.0	[0..43]	[179..34]
PA2_APIDO - Phospholipase A2 OS=Apis dorsata PE=1 SV=1	204.0	[0..43]	[179..1]
gi\|7435005 - gi\|7435005\|pir\|\|A59055 phospholipase A2 (EC 3.1.1.4), venom - Indian honeybee	203.0	[0..43]	[179..1]
PA2_APICC - Phospholipase A2 OS=Apis cerana cerana PE=2 SV=1	202.0	[0..43]	[179..1]
gi\|55244433, gi\|... - gi\|58377715\|ref\|XP_309822.2\| ENSANGP00000018245 [Anopheles gambiae str. PEST], gi\|55244433\|gb\|EAA055...	196.0	[0..47]	[179..1]

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Predicted Domain #1

Region A:
Residues: [1-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLLREAFFF GLLAMAWAFG DEAIFEDEDI YNQALPPVPH TGITVPGTKW CGPGNTAANF  60
   61 EDLGRERETD KCCRAHDHCD EIIESHGALH GLPTNTDWFP ILKCTCEQQF INCLQAVNSI 120
  121 TAKTLGRIYY GSRSRCFANG HPTTGCKQYQ EGTFRKRCIR YQVDKSKAKV WQFYDMPFFT 180
  181 IPASAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.045757
Match:	1pocA
Description:	CRYSTAL STRUCTURE OF BEE-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.44512274794048	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: