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View Structure Prediction Details

Protein: pburs-PA
Organism: Drosophila melanogaster
Length: 141 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pburs-PA.

Description E-value Query
Range
Subject
Range
gi|54645711|gb|E... - GA13626-PA [Drosophila pseudoobscura], GA13626 [Drosophila pseudoobscura pseudoobscura]
gi|125987235, gi... - gi|54645711|gb|EAL34449.1| GA13626 [Drosophila pseudoobscura pseudoobscura], gi|125987235|ref|XP_001...
255.0 [0..1] [141..1]
gi|60287223 - gi|60287223|gb|AAX18444.1| pburs [Anopheles gambiae]
222.0 [0..28] [141..81]
gi|157137149, gi... - gi|157137149|ref|XP_001663910.1| partner of burs, putative [Aedes aegypti], gi|108869790|gb|EAT34015...
215.0 [0..13] [141..18]
gi|55240882, gi|... - gi|58385239|ref|XP_313804.2| ENSANGP00000003944 [Anopheles gambiae str. PEST], gi|55240882|gb|EAA090...
209.0 [0..28] [141..28]
gi|91082075 - gi|91082075|ref|XP_966457.1| PREDICTED: similar to CG13419-PA [Tribolium castaneum]
181.0 [0..29] [137..23]
PBURS_BOMMO - Partner of bursicon OS=Bombyx mori GN=pburs PE=2 SV=1
175.0 [0..24] [141..20]
PBURS_APIME - Partner of bursicon OS=Apis mellifera GN=pburs PE=2 SV=1
171.0 [0..24] [141..28]
gi|50747914 - gi|50747914|ref|XP_426405.1| PREDICTED: similar to Ovomucin beta-subunit [Gallus gallus]
45.0 [0..15] [114..1307]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVQELLFVA AILVPQCLRA LRYSQGTGDE NCETLKSEIH LIKEEFDELG RMQRTCNADV  60
   61 IVNKCEGLCN SQVQPSVITP TGFLKECYCC RESFLKEKVI TLTHCYDPDG TRLTSPEMGS 120
  121 MDIRLREPTE CKCFKCGDFT R

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.22
Match: 1hcnB
Description: Gonadotropin B chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 4.61312396750487 bayes_pls_golite062009
growth factor activity 3.35378799007672 bayes_pls_golite062009
vascular endothelial growth factor receptor 1 binding 2.34325173014763 bayes_pls_golite062009
cytokine activity 2.25528317888709 bayes_pls_golite062009
binding 2.25218361714745 bayes_pls_golite062009
receptor serine/threonine kinase binding 2.21335536970336 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 2.08746304670185 bayes_pls_golite062009
transforming growth factor beta receptor binding 2.08746304670185 bayes_pls_golite062009
protein binding 1.92369246162193 bayes_pls_golite062009
growth factor binding 1.48640106743012 bayes_pls_golite062009
vascular endothelial growth factor receptor binding 1.40569070413521 bayes_pls_golite062009
vascular endothelial growth factor receptor 2 binding 1.35127165018698 bayes_pls_golite062009
platelet-derived growth factor receptor binding 1.33382185900586 bayes_pls_golite062009
glycosaminoglycan binding 0.894379790317675 bayes_pls_golite062009
cell surface binding 0.721690021041948 bayes_pls_golite062009
type II transforming growth factor beta receptor binding 0.594331229568324 bayes_pls_golite062009
hormone activity 0.573787538297963 bayes_pls_golite062009
heparin binding 0.46206432494086 bayes_pls_golite062009
protein dimerization activity 0.223613295842819 bayes_pls_golite062009
polysaccharide binding 0.136893519845515 bayes_pls_golite062009
protein heterodimerization activity 0.129103245482061 bayes_pls_golite062009
pattern binding 0.0498353775162013 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle