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View Structure Prediction Details

Protein: eEF1delta-PB
Organism: Drosophila melanogaster
Length: 256 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for eEF1delta-PB.

Description E-value Query
Range
Subject
Range
gi|51262090, gi|... - gi|56699438|ref|NP_083939.1| eukaryotic translation elongation factor 1 delta isoform a [Mus musculu...
336.0 [0..4] [256..385]
gi|67972082, gi|... - gi|67972082|dbj|BAE02383.1| unnamed protein product [Macaca fascicularis], gi|67969825|dbj|BAE01260....
335.0 [0..4] [256..394]
gi|51259466, gi|... - gi|61556967|ref|NP_001013122.1| eukaryotic translation elongation factor 1 delta [Rattus norvegicus]...
326.0 [0..4] [256..375]
gi|60653293, gi|... - gi|60653293|gb|AAX29341.1| eukaryotic translation elongation factor 1 delta [synthetic construct], g...
324.0 [0..4] [256..372]
gi|25453474, gi|... - gi|25453474|ref|NP_115754.2| eukaryotic translation elongation factor 1 delta isoform 1 [Homo sapien...
324.0 [0..4] [256..372]
gi|114622300 - gi|114622300|ref|XP_519999.2| PREDICTED: eukaryotic translation elongation factor 1 delta [Pan trogl...
318.0 [0..4] [256..371]

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Predicted Domain #1
Region A:
Residues: [1-100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEALDKFW ADKSRYDLAE KRFYEGPQKV TDRSHYSPLV SEIAKAREHI QNSLEKIDGV  60
   61 TLDDGLNSEL AKRLAQLEGE HKELKTQVSL LNELLTATVK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.633 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.592 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.583 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.582 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.576 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #2
Region A:
Residues: [101-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLETQLKLTN GVSKEPEVEA KKPEANDDDD DVDLFGSDSE EEDGEAARIR EERLAAYAAK  60
   61 KAKKVQIIAK SNIILDVKPW DDETDLKVME TEIRKITQDG LLWGASKFVP VAFGIQKLSI 120
  121 SCVVEDDKVS IDWLTEEIEK LEDFVQSVDI AAFNKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1b64A
Description: SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation elongation factor activity 12.3173391557088 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.81664120156021 bayes_pls_golite062009
translation regulator activity 7.77673515271111 bayes_pls_golite062009
binding 2.62647570030028 bayes_pls_golite062009
nucleic acid binding 2.32584377794188 bayes_pls_golite062009
protein binding 1.74079757896683 bayes_pls_golite062009
GTPase regulator activity 0.669814437561164 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.651746786837234 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.555069882515023 bayes_pls_golite062009
enzyme regulator activity 0.260738180200771 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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