YRC Public Data Repository - Protein Structure Prediction

Protein:	lectin-24A-PA
Organism:	Drosophila melanogaster
Length:	282 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lectin-24A-PA.

Description	E-value	Query Range	Subject Range
gi\|37813574 - gi\|37813574\|gb\|AAR04559.1\| L-SIGN variant [Homo sapiens]	190.0	[0..1]	[281..53]
CLC4M_GORGO - C-type lectin domain family 4 member M OS=Gorilla gorilla gorilla GN=CLEC4M PE=3 SV=1 gi\|27356845 - gi\|27356845\|gb\|AAL89534.1\| putative CD209L1 protein [Gorilla gorilla]	184.0	[0..1]	[281..53]
CLC4M_HYLLA - C-type lectin domain family 4 member M OS=Hylobates lar GN=CLEC4M PE=3 SV=1	178.0	[0..1]	[281..53]
CD209_PAPHA - CD209 antigen OS=Papio hamadryas GN=CD209 PE=3 SV=1	178.0	[0..1]	[281..45]
gi\|23498707 - gi\|23498707\|emb\|CAD28398.1\| putative mannose-binding C-type lectin mDC-SIGN [Macaca mulatta]	174.0	[0..1]	[281..45]
CD209_MACNE - CD209 antigen OS=Macaca nemestrina GN=CD209 PE=1 SV=1	174.0	[0..1]	[281..45]

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Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRLSVLVLN LLLVSHEFSA GTAKIEIQPL PALCNGYCFP TLKPVMEYVA IHQDKWNTCT  60
   61 EILANEARKD QIQLNIQLDA LKADVSNIKA SQLSKDEKLD RMEREQFAMH ESLETINRYL 120
  121 TVKLDRTKLQ LEAIKNTMDY MKAQMDGYFS AINGVQCLQP GFEKIGDRYF YIEEDVELNW 180
  181 LDAQAKCRRM GGHLASIKTK QEFDAIVEKL DDSKSYFLGV NENTKTGDFV SAASGKSCLY 240
  241 HEWGPGEPHH NNDQERCVSI LRKLMHVGNC TYEKRFICQY GI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.221849
Match:	1sl6A
Description:	Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits