YRC Public Data Repository - Protein Structure Prediction

Protein:	GMFG_RAT
Organism:	Rattus norvegicus
Length:	142 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GMFG_RAT.

Description	E-value	Query Range	Subject Range
gi\|48374972 - gi\|48374972\|gb\|AAT42170.1\| putative actin depolymerizing factor [Sorghum bicolor]	172.0	[0..1]	[137..325]
ADF4_ARATH - Actin-depolymerizing factor 4 OS=Arabidopsis thaliana GN=ADF4 PE=1 SV=2	159.0	[0..1]	[138..1]
ADF1_PETHY - Actin-depolymerizing factor 1 OS=Petunia hybrida GN=ADF1 PE=2 SV=1	158.0	[0..1]	[137..1]
gi\|68166241 - gi\|68166241\|gb\|AAY88048.1\| actin depolymerizing factor [Gossypium hirsutum]	157.0	[0..1]	[137..1]
gi\|110681458 - gi\|110681458\|emb\|CAL25339.1\| actin-depolymerizing factor [Platanus x acerifolia]	156.0	[0..1]	[139..1]
gi\|91206452, gi\|... - gi\|91206452\|ref\|NP_001035136.1\| hypothetical protein LOC677752 [Danio rerio], gi\|90112039\|gb\|AAI1433...	156.0	[0..1]	[142..1]
gi\|71895903, gi\|... - gi\|71895903\|ref\|NP_001025651.1\| gmfg protein [Xenopus (Silurana) tropicalis], gi\|60649474\|gb\|AAH9170...	156.0	[0..1]	[142..1]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSLVVCDV DPELKETLRK FRFRKETNNA AIIMKVDKDR QMVVLEDEFQ NVSPEELKLE  60
   61 LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNR LVQIAELTKV 120
  121 FEIRTTDDLN ETWLKEKLAF FR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.69897
Match:	1vkkA
Description:	Crystal structure of Glia maturation factor-gamma (GMFG) from Mus musculus at 1.50 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.84811181543046	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.12748339390054	bayes_pls_golite062009
protein kinase activity	2.04816578082974	bayes_pls_golite062009
kinase activity	2.02850332510521	bayes_pls_golite062009
cytoskeletal protein binding	1.93205806704503	bayes_pls_golite062009
protein binding	1.87981807141519	bayes_pls_golite062009
actin binding	1.81852351993606	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.80141476920505	bayes_pls_golite062009
transferase activity	1.29476796563251	bayes_pls_golite062009
protein tyrosine kinase activity	0.445404590790816	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: