YRC Public Data Repository - Protein Structure Prediction

Protein:	MIA_RAT
Organism:	Rattus norvegicus
Length:	130 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIA_RAT.

Description	E-value	Query Range	Subject Range
MIA_BOVIN - Melanoma-derived growth regulatory protein OS=Bos taurus GN=MIA PE=2 SV=1	130.0	[0..1]	[130..1]
MIA_MOUSE - Melanoma-derived growth regulatory protein OS=Mus musculus GN=Mia PE=2 SV=2	125.0	[0..1]	[130..1]
gi\|73948308 - gi\|73948308\|ref\|XP_541610.2\| PREDICTED: similar to Melanoma derived growth regulatory protein precur...	124.0	[0..1]	[130..1]
gi\|60832750 - gi\|60832750\|gb\|AAX37023.1\| melanoma inhibitory activity [synthetic construct]	123.0	[0..1]	[130..1]
MIA - melanoma inhibitory activity gi\|55649185, gi\|... - gi\|55649185\|ref\|XP_512675.1\| PREDICTED: melanoma inhibitory activity isoform 3 [Pan troglodytes], gi... gi\|61361652 - gi\|61361652\|gb\|AAX42081.1\| melanoma inhibitory activity [synthetic construct]	123.0	[0..1]	[130..1]
gi\|109124844, gi... - gi\|109124844\|ref\|XP_001098701.1\| PREDICTED: melanoma inhibitory activity isoform 2 [Macaca mulatta],...	119.0	[0..1]	[130..1]
gi\|110767215 - gi\|110767215\|ref\|XP_393062.3\| PREDICTED: similar to intersectin 2 isoform 3 [Apis mellifera]	107.0	[0..9]	[127..1139]

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Predicted Domain #1

Region A:
Residues: [1-130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCSPVLLGI VILSVFSGLS RADRAMPKLA DRKLCADEEC SHPISMAVAL QDYVAPDCRF  60
   61 LTIYRGQVVY VFSKLKGRGR LFWGGSVQGD YYGDLAAHLG YFPSSIVRED LTLKPGKVDM 120
  121 KTDEWDFYCQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.0
Match:	1i1jA
Description:	Melanoma inhibitory activity protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	2.03813744146232	bayes_pls_golite062009
binding	2.0198140785578	bayes_pls_golite062009
receptor binding	1.46964167495514	bayes_pls_golite062009
cytoskeletal protein binding	0.313587086905048	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: