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View Structure Prediction Details

Protein: bre-1
Organism: Caenorhabditis elegans
Length: 382 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bre-1.

Description E-value Query
Range
Subject
Range
gi|49529344, gi|... - gi|50083368|ref|YP_044878.1| dTDP-D-glucose-4,6-dehydratase [Acinetobacter sp. ADP1], gi|49529344|em...
320.0 [0..34] [377..2]

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Predicted Domain #1
Region A:
Residues: [1-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSSAEQGLE ACIGMSHEVS TTPAAELAAF RARKVALITG ISGQDGSYLA ELLLSKGYKV  60
   61 HGIIRRSSSF NTARIEHLYS NPITHHGDSS FSLHYGDMTD SSCLIKLIST IEPTEVYHLA 120
  121 AQSHVKVSFD LPEYTAEVDA VGTLRLLDAI HACRLTEKVR FYQASTSELY GKVQEIPQSE 180
  181 KTPFYPRSPY AVAKMYGYWI VVNYREAYNM FACNGILFNH ESPRRGETFV TRKITRSVAK 240
  241 ISLGQQESIE LGNLSALRDW GHAREYVEAM WRILQHDSPD DFVIATGKQF SVREFCNLAF 300
  301 AEIGEVLQWE GEGVEEVGKN KDGVIRVKVS PKYYRPTEVE TLLGNAEKAK KTLGWEAKVT 360
  361 VPELVKEMVA SDIILMKSNP MA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.69897
Match: 1t2aA
Description: Crystal structure of human GDP-D-mannose 4,6-dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle