YRC Public Data Repository - Protein Structure Prediction

Protein:	GSTK1_RAT
Organism:	Rattus norvegicus
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSTK1_RAT.

Description	E-value	Query Range	Subject Range
gi\|50729460 - gi\|50729460\|ref\|XP_416525.1\| PREDICTED: similar to Glutathione S-transferase kappa 1 [Gallus gallus]	192.0	[0..3]	[226..1]
gi\|73978758 - gi\|73978758\|ref\|XP_532742.2\| PREDICTED: similar to Glutathione S-transferase kappa 1 (GST 13-13) (Gl...	190.0	[0..1]	[226..1]
gi\|109069349 - gi\|109069349\|ref\|XP_001087577.1\| PREDICTED: glutathione S-transferase kappa 1 [Macaca mulatta]	189.0	[0..1]	[226..1]
gi\|114616503 - gi\|114616503\|ref\|XP_519446.2\| PREDICTED: glutathione transferase kappa 1 isoform 5 [Pan troglodytes]	189.0	[0..1]	[226..1]
GSTK1 - glutathione S-transferase kappa 1	188.0	[0..1]	[226..1]
gi\|148235618, gi... - gi\|77748129\|gb\|AAI06345.1\| MGC130886 protein [Xenopus laevis], gi\|148235618\|ref\|NP_001089691.1\| hypo...	187.0	[0..1]	[222..1]
GSTK1_MOUSE - Glutathione S-transferase kappa 1 OS=Mus musculus GN=Gstk1 PE=1 SV=3	184.0	[0..1]	[226..1]
gi\|86826515, gi\|... - gi\|86826515\|gb\|AAI12480.1\| Glutathione S-transferase kappa 1 [Bos taurus], gi\|118601826\|ref\|NP_00107...	184.0	[0..1]	[226..1]
gi\|56556571, gi\|... - gi\|58332184\|ref\|NP_001011244.1\| glutathione S-transferase kappa 1 [Xenopus (Silurana) tropicalis], g...	184.0	[0..1]	[222..1]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPAPRVLEL FYDVLSPYSW LGFEVLCRYQ HLWNIKLKLR PALLAGIMKD SGNQPPAMVP  60
   61 HKGQYILKEI PLLKQLFQVP MSVPKDFFGE HVKKGTVNAM RFLTAVSMEQ PEMLEKVSRE 120
  121 LWMRIWSRDE DITESQNILS AAEKAGMATA QAQHLLNKIS TELVKSKLRE TTGAACKYGA 180
  181 FGLPTTVAHV DGKTYMLFGS DRMELLAYLL GEKWMGPVPP TLNARL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.0
Match:	1r4wA
Description:	Crystal structure of Mitochondrial class kappa glutathione transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutathione transferase activity	3.10261229787796	bayes_pls_golite062009
antioxidant activity	2.98988279939823	bayes_pls_golite062009
glutathione binding	2.53131331487579	bayes_pls_golite062009
glutathione peroxidase activity	2.45655797002775	bayes_pls_golite062009
peroxidase activity	2.09720157676308	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.09720157676308	bayes_pls_golite062009
oxidoreductase activity	1.66622364190158	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.44229450804826	bayes_pls_golite062009
disulfide oxidoreductase activity	0.713619215118063	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.15984522114548	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: