YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|114601775, gi...
Organism:	Pan troglodytes
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114601775, gi....

Description	E-value	Query Range	Subject Range
gi\|73971330 - gi\|73971330\|ref\|XP_538635.2\| PREDICTED: similar to H2A histone family, member Y isoform 3 [Canis fam...	0.0	[1..372]	[41..412]
gi\|12643340, gi\|... - gi\|3493529\|gb\|AAC33433.1\| histone macroH2A1.2 [Homo sapiens], gi\|12643340\|sp\|O75367\|H2AY_HUMAN Core ...	4.0E-99	[1..372]	[1..372]
gi\|87578157, gi\|... - gi\|87578157\|gb\|AAI13288.1\| H2A histone family, member Y [Bos taurus], gi\|114052404\|ref\|NP_001039805....	5.0E-99	[1..372]	[1..371]
H2AY_RAT - Core histone macro-H2A.1 OS=Rattus norvegicus GN=H2afy PE=1 SV=4	8.0E-99	[1..372]	[1..371]
H2AY_MOUSE - Core histone macro-H2A.1 OS=Mus musculus GN=H2afy PE=1 SV=3	1.0E-98	[1..372]	[1..372]
gi\|114601789 - gi\|114601789\|ref\|XP_001168507.1\| PREDICTED: similar to H2AFY protein isoform 6 [Pan troglodytes]	4.0E-98	[1..372]	[1..380]
gi\|542149408\|ref... - PREDICTED: core histone macro-H2A.1-like isoform X1 [Zonotrichia albicollis] gi\|224068058 - gi\|224068058\|ref\|XP_002187530.1\| PREDICTED: H2A histone family, member Y [Taeniopygia guttata] H2AY_CHICK - Core histone macro-H2A.1 OS=Gallus gallus GN=H2AFY PE=1 SV=3	1.0E-97	[1..372]	[1..372]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRGGKKKS TKTSRSAKAG VIFPVGRMLR YIKKGHPKYR IGVGAPVYMA AVLEYLTAEI  60
   61 LELAGNAARD NKKGRVTPRH ILLAVANDEE LNQLLKGVTI ASGGVLPNIH PELLAKKRGS 120
  121 KGKLEAIITP P

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.045757
Match:	1u35C
Description:	Crystal structure of the nucleosome core particle containing the histone domain of macroH2A
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [132-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAKKAKSPSQ KKPVSKKAGG KKGARKSKKK QGEVSKAASA DSTTEGTPAD GFTVLSTKSL  60
   61 FLGQKLNLIH SEISNLAGFE VEAIINPTNA DIDLKDDLGN TLEKKGGKEF VEAVLELRKK 120
  121 NGPLEVAGAA VSAGHGLPAK FVIHCNSPVW GADKCEELLE KTVKNCLALA DDKKLKSIAF 180
  181 PSIGSGRNGF PKQTAAQLIL KAISSYFVST MSSSIKTVYF VLFDSESIGI YVQEMAKLDA 240
  241 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.69897
Match:	1zr5A
Description:	Crystal structure of the macro-domain of human core histone variant macroH2A1.2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits