YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|123995087, gi...
Organism:	synthetic construct
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123995087, gi....

Description	E-value	Query Range	Subject Range
gi\|50745196 - gi\|50745196\|ref\|XP_420017.1\| PREDICTED: similar to Stathmin 4 (Stathmin-like protein B3) (RB3) [Gall...	1.0E-80	[1..216]	[105..292]
gi\|148704047 - gi\|148704047\|gb\|EDL35994.1\| stathmin-like 4, isoform CRA_b [Mus musculus] gi\|149030331, gi... - ref\|XP_341342.1\| stathmin-like-protein RB3 [Rattus norvegicus], gi\|2585995\|gb\|AAC95063.1\| stathmin-...	7.0E-80	[1..216]	[1..216]
gi\|149746233 - gi\|149746233\|ref\|XP_001494785.1\| PREDICTED: similar to Stathmin-like 4 isoform 1 [Equus caballus] gi\|73993688 - gi\|73993688\|ref\|XP_849048.1\| PREDICTED: similar to stathmin-like-protein RB3 isoform 2 [Canis famili...	6.0E-79	[1..216]	[1..216]
STMN4_MOUSE - Stathmin-4 OS=Mus musculus GN=Stmn4 PE=2 SV=1 STMN4_RAT - Stathmin-4 OS=Rattus norvegicus GN=Stmn4 PE=1 SV=1	8.0E-67	[1..216]	[1..189]
gi\|112418604, gi... - gi\|118404922\|ref\|NP_001072489.1\| stathmin-like-protein RB3 [Xenopus (Silurana) tropicalis], gi\|11241...	3.0E-63	[1..216]	[1..189]
gi\|51593492, gi\|... - gi\|51593492\|gb\|AAH78521.1\| MGC85341 protein [Xenopus laevis], gi\|148230485\|ref\|NP_001087294.1\| MGC85...	2.0E-62	[1..216]	[1..189]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLAAYKEKM KELPLVSLFC SCFLADPLNK SSYKYEGWCG RQCRRKDESQ RKDSADWRER  60
   61 RAQADTVDLN WCVISDMEVI ELNKCTSGQS FEVILKPPSF DGVPEFNASL PRRRDPSLEE 120
  121 IQKKLEAAEE RRKYQEAELL KHLAEKREHE REVIQKAIEE NNNFIKMAKE KLAQKMESNK 180
  181 ENREAHLAAM LERLQEKDKH AEEVRKNKEL KEEASR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.522879
Match:	1sa1E
Description:	TUBULIN-PODOPHYLLOTOXIN: STATHMIN-LIKE DOMAIN COMPLEX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tubulin binding	6.62779017447975	bayes_pls_golite062009
microtubule binding	5.64548039780746	bayes_pls_golite062009
cytoskeletal protein binding	5.28582290763985	bayes_pls_golite062009
protein binding	2.51615225301602	bayes_pls_golite062009
binding	2.22547233326175	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: