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View Structure Prediction Details

Protein: FGF1_RAT
Organism: Rattus norvegicus
Length: 155 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FGF1_RAT.

Description E-value Query
Range		 Subject
Range
gi|226785 - gi|226785|prf||1605206A acidic fibroblast growth factor
 218.0 [0..1] [155..2]
gi|60654519 - gi|60654519|gb|AAX29950.1| fibroblast growth factor 1 [synthetic construct]
 218.0 [0..1] [155..1]
gi|56403619 - gi|56403619|emb|CAI29610.1| hypothetical protein [Pongo abelii]
gi|197098138 - gi|197098138|ref|NP_001127073.1| fibroblast growth factor 1 (acidic) [Pongo abelii]
 218.0 [0..1] [155..60]
gi|149726242, gi... - gi|255522909|ref|NP_001157358.1| fibroblast growth factor 1 (acidic) [Equus caballus], gi|149726242|...
gi|109079121, gi... - gi|109079121|ref|XP_001096351.1| PREDICTED: fibroblast growth factor 1 (acidic) isoform 4 [Macaca mu...
tr|M3WAU6|M3WAU6... - Fibroblast growth factor OS=Felis catus GN=FGF1 PE=3 SV=1
 217.0 [0..1] [155..1]
FGF1_MESAU - Fibroblast growth factor 1 OS=Mesocricetus auratus GN=FGF1 PE=2 SV=1
 216.0 [0..1] [155..1]
gi|73949448 - gi|73949448|ref|XP_849274.1| PREDICTED: similar to Heparin-binding growth factor 1 precursor (HBGF-1...
 215.0 [0..1] [155..1]
FGF1_BOVIN - Fibroblast growth factor 1 OS=Bos taurus GN=FGF1 PE=1 SV=2
 213.0 [0..1] [155..1]

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Predicted Domain #1
Region A:
Residues: [1-155] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGEITTFA ALTERFNLPL GNYKKPKLLY CSNGGHFLRI LPDGTVDGTR DRSDQHIQLQ  60
   61 LSAESAGEVY IKGTETGQYL AMDTEGLLYG SQTPNEECLF LERLEENHYN TYTSKKHAEK 120
  121 NWFVGLKKNG SCKRGPRTHY GQKAILFLPL PVSSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.30103
Match: 1rmlA
Description: NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fibroblast growth factor receptor binding 5.68976822724664 bayes_pls_golite062009
growth factor activity 5.6790632853895 bayes_pls_golite062009
receptor binding 4.8109037277027 bayes_pls_golite062009
cytokine activity 3.72907359340826 bayes_pls_golite062009
protein binding 2.99442649109752 bayes_pls_golite062009
binding 2.90110516688922 bayes_pls_golite062009
glycosaminoglycan binding 2.49177421879896 bayes_pls_golite062009
heparin binding 2.1616134585534 bayes_pls_golite062009
polysaccharide binding 1.81686028727894 bayes_pls_golite062009
interleukin-1 receptor binding 0.8084616632765 bayes_pls_golite062009
pattern binding 0.323275442862789 bayes_pls_golite062009
nerve growth factor receptor binding 0.308245352535379 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle