YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|114638083
Organism:	Pan troglodytes
Length:	619 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114638083.

Description	E-value	Query Range	Subject Range
gi\|4406524 - gi\|4406524\|gb\|AAD20016.1\| tip-associated protein TAP [Homo sapiens]	0.0	[1..619]	[1..619]
NXF1_PONAB - Nuclear RNA export factor 1 OS=Pongo abelii GN=NXF1 PE=3 SV=1 NXF1_PONPY - Nuclear RNA export factor 1 - Pongo pygmaeus (Orangutan)	0.0	[1..619]	[1..626]
gi\|109105694 - gi\|109105694\|ref\|XP_001115982.1\| PREDICTED: similar to nuclear RNA export factor 1 isoform 5 [Macaca...	0.0	[1..619]	[1..621]
NXF1_RAT - Nuclear RNA export factor 1 OS=Rattus norvegicus GN=Nxf1 PE=2 SV=1	0.0	[1..619]	[1..618]
gi\|26346549 - gi\|26346549\|dbj\|BAC36922.1\| unnamed protein product [Mus musculus]	0.0	[1..619]	[1..618]
gi\|114638087 - gi\|114638087\|ref\|XP_508503.2\| PREDICTED: nuclear RNA export factor 1 isoform 10 [Pan troglodytes]	0.0	[6..619]	[2..615]
NXF1_BOVIN - Nuclear RNA export factor 1 OS=Bos taurus GN=NXF1 PE=2 SV=1	0.0	[1..619]	[1..620]

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Predicted Domain #1

Region A:
Residues: [1-93]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEGKSYSE HDDERVNFPQ RKKKGRGPFR WKYGEGNRRS GRGGSGIRSS RLEEDDGDVA  60
   61 MSDAQDGPRV RYNPYTTRPN RRGDTWHDRD RIH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [94-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTVRRDRAPP ERGGAGTSQD GTSKNWFKIT IPYGRKYDKA WLLSMIQSKC SVPFTPIEFH  60
   61 YENTRAQFFV EDASTASALK AVNYKILDRE NRRISIII

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.30103
Match:	1kooA
Description:	mRNA export factor tap
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [192-487]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSAPPHTIL NELKPEQVEQ LKLIMSKRYD GSQQALDLKG LRSDPDLVAQ NIDVVLNRRS  60
   61 CMAATLRIIE ENIPELLSLN LSNNRLYRLD DMSSIVQKAP NLKILNLSGN ELKSERELDK 120
  121 IKGLKLEELW LDGNSLCDTF RDQSTYISAI RERFPKLLRL DGHELPPPIA FDVEAPTTLP 180
  181 PCKGSYFGTE NLKSLVLHFL QQYYAIYDSG DRQGLLDAYH DGACCSLSIP FIPQNPARSS 240
  241 LAEYFKDSRN VKKLKDPTLR FRLLKHTRLN VVAFLNELPK TQHDVNSFVV DISAQT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.69897
Match:	2id5A
Description:	No description for 2id5A was found.

Predicted Domain #4

Region A:
Residues: [488-540]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STLLCFSVNG VFKEVDGKSR DSLRAFTRTF IAVPASNSGL CIVNDELFVR NAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.69897
Match:	1q40B
Description:	Crystal structure of the C. albicans Mtr2-Mex67 M domain complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleocytoplasmic transporter activity	4.11811310168752	bayes_pls_golite062009
protein transporter activity	2.82714862961769	bayes_pls_golite062009
binding	2.08734227778958	bayes_pls_golite062009
RNA binding	1.98983420561953	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
protein transmembrane transporter activity	1.79601989348889	bayes_pls_golite062009
mRNA binding	1.39091688795726	bayes_pls_golite062009
protein binding	1.36536670483288	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.45916069455408	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.45916069455408	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [541-619]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEEIQRAFAM PAPTPSSSPV PTLSPEQQEM LQAFSTQSGM NLEWSQKCLQ DNNWDYTRSA  60
   61 QAFTHLKAKG EIPEVAFMK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.045757
Match:	1jkgB
Description:	NTF2-like domain of Tip associating protein, TAP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleocytoplasmic transporter activity	4.11811310168752	bayes_pls_golite062009
protein transporter activity	2.82714862961769	bayes_pls_golite062009
binding	2.08734227778958	bayes_pls_golite062009
RNA binding	1.98983420561953	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
protein transmembrane transporter activity	1.79601989348889	bayes_pls_golite062009
mRNA binding	1.39091688795726	bayes_pls_golite062009
protein binding	1.36536670483288	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.45916069455408	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.45916069455408	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: