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View Structure Prediction Details

Protein: gi|118097222
Organism: Gallus gallus
Length: 437 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|118097222.

Description E-value Query
Range		 Subject
Range
gi|31559959, gi|... - gi|31559959|ref|NP_659115.2| eukaryotic translation termination factor 1 [Mus musculus], gi|26340352...
 0.0 [1..437] [1..437]
ERF1_PONPY - Eukaryotic peptide chain release factor subunit 1 - Pongo pygmaeus (Orangutan)
ERF1_PONAB - Eukaryotic peptide chain release factor subunit 1 OS=Pongo abelii GN=ETF1 PE=2 SV=3
 0.0 [1..437] [1..437]
ERF1_XENTR - Eukaryotic peptide chain release factor subunit 1 OS=Xenopus tropicalis GN=etf1 PE=2 SV=1
 0.0 [1..437] [1..437]
ERF1_XENLA - Eukaryotic peptide chain release factor subunit 1 OS=Xenopus laevis GN=etf1 PE=2 SV=1
 0.0 [1..437] [1..437]
gi|30174452, gi|... - gi|31236922|ref|XP_319502.1| AGAP010310-PA [Anopheles gambiae str. PEST], gi|30174452|gb|EAA14616.2|...
AGAP010310-PA - Eukaryotic peptide chain release factor subunit|protein_coding|3L:66666:82270:-1|gene:AGAP010310
 0.0 [1..437] [1..438]
gi|220944832, gi... - gi|220954670|gb|ACL89878.1| eRF1-PA [synthetic construct], gi|220944832|gb|ACL84959.1| eRF1-PA [synt...
gi|194118161, gi... - gi|195160369|ref|XP_002021048.1| GL25132 [Drosophila persimilis], gi|194118161|gb|EDW40204.1| GL2513...
eRF1-PC, eRF1-PB... - The gene eukaryotic release factor 1 is referred to in FlyBase by the symbol Dmel\eRF1 (CG5605, FBgn...
 0.0 [1..437] [1..438]

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Predicted Domain #1
Region A:
Residues: [1-437] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADDPSAADR NVEIWKIKKL IKSLEAARGN GTSMISLIIP PKDQISRVAK MLADEFGTAS  60
   61 NIKSRVNRLS VLGAITSVQQ RLKLYNKVPP NGLVVYCGTI VTEEGKEKKV NIDFEPFKPI 120
  121 NTSLYLCDNK FHTEALTALL SDDSKFGFIV IDGSGALFGT LQGNTREVLH KFTVDLPKKH 180
  181 GRGGQSALRF ARLRMEKRHN YVRKVAETAV QLFISGDKVN VAGLVLAGSA DFKTELSQSD 240
  241 MFDQRLQSKV LKLVDISYGG ENGFNQAIEL STEVLSNVKF IQEKKLIGRY FDEISQDTGK 300
  301 YCFGVEDTLK ALEMGAVEIL IVYENLDIMR YVLHCQGTEE EKILYLTPEQ EKDKSHFTDK 360
  361 ETGQEHELIE SMPLLEWFAN NYKKFGATLE IVTDKSQEGS QFVKGFGGIG GILRYRVDFQ 420
  421 GMEYQGGDDE FFDLDDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1dt9A
Description: Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation release factor activity 11.5102558694213 bayes_pls_golite062009
translation termination factor activity 11.4768548464911 bayes_pls_golite062009
translation release factor activity, codon specific 7.66455753522311 bayes_pls_golite062009
structural constituent of ribosome 2.97154934968642 bayes_pls_golite062009
nucleic acid binding 2.70960972397471 bayes_pls_golite062009
structural molecule activity 2.64319832043379 bayes_pls_golite062009
binding 2.24516466558786 bayes_pls_golite062009
translation regulator activity 1.83257472130927 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.81472167858216 bayes_pls_golite062009
RNA binding 1.59103459949328 bayes_pls_golite062009
mRNA binding 0.607146672130391 bayes_pls_golite062009
protein binding 0.381324299701367 bayes_pls_golite062009
catalytic activity 0.264002643439785 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle