YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|114598928
Organism:	Pan troglodytes
Length:	259 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114598928.

Description	E-value	Query Range	Subject Range
gi\|60653549, gi\|... - gi\|60653551\|gb\|AAX29469.1\| steroid-5-alpha-reductase alpha polypeptide 1 [synthetic construct], gi\|6...	2.0E-71	[1..259]	[1..259]
gi\|109076702 - gi\|109076702\|ref\|XP_001083405.1\| PREDICTED: similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Ster... S5A1_MACFA - 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS=Macaca fascicularis GN=SRD5A1 PE=1 SV=1	2.0E-67	[1..259]	[1..263]
S5A1_RAT - 3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS=Rattus norvegicus GN=Srd5a1 PE=1 SV=2 gi\|1336835 - gi\|1336835\|gb\|AAB36218.1\| type I 5 alpha-reductase [Rattus sp.]	3.0E-64	[1..258]	[1..258]
gi\|87044895, gi\|... - gi\|87044895\|ref\|NP_780492.2\| steroid-5-alpha-reductase 1 [Mus musculus], gi\|51259759\|gb\|AAH79863.1\| ...	6.0E-63	[5..258]	[1..254]
gi\|74003097 - gi\|74003097\|ref\|XP_535799.2\| PREDICTED: similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Steroid ...	1.0E-59	[5..259]	[1..255]
gi\|60551245 - gi\|60551245\|gb\|AAH91002.1\| Gpsn2 protein [Xenopus tropicalis]	6.0E-55	[41..258]	[114..345]
gi\|114598930 - gi\|114598930\|ref\|XP_001144414.1\| PREDICTED: steroid-5-alpha-reductase 1 isoform 1 [Pan troglodytes] gi\|6523819 - gi\|6523819\|gb\|AAF14869.1\|AF113128_1 steroid-5-alpha-reductase isoform [Homo sapiens]	3.0E-54	[1..259]	[1..211]

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Predicted Domain #1

Region A:
Residues: [1-107]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATATGVAEE RLLAALAYLQ CAVGCAVFAR NRQTNSVYGR HALPSHRLRV PARAAWVVQE  60
   61 LPSLALPLYQ YASESAPRLR SAPNCILLAM FLVHYGHRCL IYPFLMR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.321	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.315	N/A	N/A	a.5.3	N-terminal domain of phosphatidylinositol transfer protein sec14p
View	Download	0.297	N/A	N/A	a.39.1	EF-hand
View	Download	0.284	N/A	N/A	a.44.1	Disulphide-bond formation facilitator (DSBA), insertion domain
View	Download	0.283	N/A	N/A	a.44.1	Disulphide-bond formation facilitator (DSBA), insertion domain

Predicted Domain #2

Region A:
Residues: [108-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGKPMPLLAC TMAIMFCTCN GYLQSRYLSH CAVYADDWVT DPRFLIGFGL WLTGMLINIH  60
   61 SDHILRNLRK PGDTGYKIPR GGLFEYVTAA NYFGEIMEWC GYALASWSVQ GAAFAFFTFC 120
  121 FLSGRAKEHH EWYLRKFEEY PKFRKIIIPF LF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	104.744727
Match:	PF02544.7
Description:	No description for PF02544.7 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits