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View Structure Prediction Details

Protein: gi|123980634, gi...
Organism: synthetic construct
Length: 260 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123980634, gi....

Description E-value Query
Range		 Subject
Range
gi|80477642, gi|... - gi|80477642|gb|AAI08581.1| MGC131075 protein [Xenopus laevis], gi|148234718|ref|NP_001089873.1| hypo...
 2.0E-63 [1..260] [1..260]
gi|74227220 - gi|74227220|dbj|BAE38377.1| unnamed protein product [Mus musculus]
 2.0E-63 [1..260] [1..260]
gi|66911967 - gi|66911967|gb|AAH97301.1| Hagh protein [Rattus norvegicus]
 2.0E-63 [1..260] [45..304]
gi|73959572 - gi|73959572|ref|XP_537013.2| PREDICTED: similar to hydroxyacyl glutathione hydrolase [Canis familiar...
 5.0E-63 [1..260] [50..309]
HAGH - hydroxyacylglutathione hydrolase
 8.0E-63 [1..260] [49..308]
GLO2_BOVIN - Hydroxyacylglutathione hydrolase, mitochondrial OS=Bos taurus GN=HAGH PE=2 SV=3
 1.0E-62 [1..260] [49..308]
GLO2_CHICK - Hydroxyacylglutathione hydrolase, mitochondrial OS=Gallus gallus GN=HAGH PE=2 SV=1
 1.0E-62 [1..260] [51..310]

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Predicted Domain #1
Region A:
Residues: [1-260] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEVLPALT DNYMYLVIDD ETKEAAIVDP VQPQKVVDAA RKHGVKLTTV LTTHHHWDHA  60
   61 GGNEKLVKLE SGLKVYGGDD RIGALTHKIT HLSTLQVGSL NVKCLATPCH TSGHICYFVS 120
  121 KPGGSEPPAV FTGDTLFVAG CGKFYEGTAD EMCKALLEVL GRLPPDTRVY CGHEYTINNL 180
  181 KFARHVEPGN AAIREKLAWA KEKYSIGEPT VPSTLAEEFT YNPFMRVREK TVQQHAGETD 240
  241 PVTTMRAVRR EKDQFKMPRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.0
Match: 1qh3A
Description: Glyoxalase II (hydroxyacylglutathione hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydroxyacylglutathione hydrolase activity 3.53012507604564 bayes_pls_golite062009
catalytic activity 0.941400907161877 bayes_pls_golite062009
binding 0.900972948435178 bayes_pls_golite062009
thiolester hydrolase activity 0.802604883362264 bayes_pls_golite062009
hydrolase activity 0.021392930321391 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle