YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|124500373, gi...
Organism:	Escherichia coli B
Length:	373 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|124500373, gi....

Description	E-value	Query Range	Subject Range
gi\|10946239 - gi\|10946239\|gb\|AAG24813.1\| GDP-D-mannose 4,6-dehydratase [Salmonella typhimurium] gi\|62180680, gi\|... - gi\|62180680\|ref\|YP_217097.1\| GDP-D-mannose dehydratase in colanic acid gene cluster [Salmonella ente... gi\|198245271, gi... - gi\|198245271\|ref\|YP_002216196.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|204321536, gi... - gi\|204928992\|ref\|ZP_03220135.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica ser... gi\|194738147, gi... - gi\|194738147\|ref\|YP_002115198.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|197214539, gi... - gi\|197250836\|ref\|YP_002147067.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|205344976, gi... - gi\|205344976\|gb\|EDZ31740.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|194450416, gi... - gi\|194450416\|ref\|YP_002046159.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|168259587, gi... - gi\|205351085\|gb\|EDZ37716.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|195631295, gi... - gi\|195631295\|gb\|EDX49855.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|197290635, gi... - gi\|197290635\|gb\|EDY29990.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|168242182, gi... - gi\|205338307\|gb\|EDZ25071.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|205324083, gi... - gi\|205324083\|gb\|EDZ11922.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|10946239\|gb\|A... - GDP-D-mannose 4,6-dehydratase [Salmonella typhimurium] gi\|205330524, gi... - gi\|205330524\|gb\|EDZ17288.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serovar... gi\|161362575, gi... - gi\|161613211\|ref\|YP_001587176.1\| hypothetical protein SPAB_00921 [Salmonella enterica subsp. enteric... lcl\|NC_016856.1_... - [gene=gmd] [protein=GDP-D-mannose dehydratase] [protein_id=YP_005238145.1] [location=complement(2244... gi\|207857545, gi... - gi\|207857545\|ref\|YP_002244196.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|238912538 - gi\|238912538\|ref\|ZP_04656375.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica ser... gi\|16420642, gi\|... - gi\|16765439\|ref\|NP_461054.1\| GDP-D-mannose dehydratase [Salmonella typhimurium LT2], gi\|16420642\|gb\|...	349.0	[0..1]	[373..1]
gi\|191169555, gi... - gi\|75227097\|ref\|ZP_00713917.1\| COG1089: GDP-D-mannose dehydratase [Escherichia coli B7A], gi\|1911695...	349.0	[0..1]	[373..1]
gi\|54401428 - gi\|54401428\|gb\|AAV34512.1\| GDP-mannose dehydratase [Salmonella enterica subsp. enterica serovar Urba...	348.0	[0..1]	[372..1]
gi\|213650330 - gi\|213650330\|ref\|ZP_03380383.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica ser... gi\|16761040 - gi\|16761040\|ref\|NP_456657.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serova... gi\|25319271, gi\|... - gi\|25319271\|pir\|\|AB0769 GDPmannose 4,6-dehydratase (EC 4.2.1.47) - Salmonella enterica subsp. enteri... gi\|213622920 - gi\|213622920\|ref\|ZP_03375703.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica ser... gi\|29136890, gi\|... - gi\|29141264\|ref\|NP_804606.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serova... gi\|213425535 - gi\|213425535\|ref\|ZP_03358285.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica ser...	348.0	[0..1]	[373..1]
gi\|197361918, gi... - gi\|197361918\|ref\|YP_002141555.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica se... gi\|56127247, gi\|... - gi\|56412990\|ref\|YP_150065.1\| GDP-mannose 4,6-dehydratase [Salmonella enterica subsp. enterica serova...	348.0	[0..1]	[373..1]
gi\|56159886, gi\|... - gi\|56384974\|gb\|AAV85954.1\| Gmd [Escherichia coli], gi\|56159886\|gb\|AAV80750.1\| GDP-mannose 4,6-dehydr... gi\|215487261, gi... - gi\|215487261\|ref\|YP_002329692.1\| GDP-D-mannose dehydratase, NAD(P)-binding [Escherichia coli O127:H6...	348.0	[0..1]	[373..1]
gi\|110806020, gi... - gi\|110806020\|ref\|YP_689540.1\| GDP-D-mannose dehydratase [Shigella flexneri 5 str. 8401], gi\|11061556...	347.0	[0..1]	[373..1]
gi\|54401438 - gi\|54401438\|gb\|AAV34519.1\| GDP-mannose dehydratase [Salmonella enterica subsp. salamae serovar Green...	347.0	[0..1]	[372..1]
gi\|110642263, gi... - gi\|110642263\|ref\|YP_669993.1\| GDP-mannose 4,6-dehydratase [Escherichia coli 536], gi\|110343855\|gb\|AB... gi\|75242875, gi\|... - gi\|75242875\|ref\|ZP_00726581.1\| COG1089: GDP-D-mannose dehydratase [Escherichia coli F11], gi\|1911699...	347.0	[0..1]	[373..1]
gi\|194431490, gi... - gi\|83571241\|ref\|ZP_00922682.1\| COG1089: GDP-D-mannose dehydratase [Shigella dysenteriae 1012], gi\|19...	346.0	[0..1]	[373..1]

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Predicted Domain #1

Region A:
Residues: [1-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVALITGV TGQDGSYLAE FLLEKGYEVH GIKRRASSFN TERVDHIYQD PHTCNPKFHL  60
   61 HYGDLSDTSN LTRILREVQP DEVYNLGAMS HVAVSFESPE YTADVDAMGT LRLLEAIRFL 120
  121 GLEKKTRFYQ ASTSELYGLV QEIPQKETTP FYPRSPYAVA KLYAYWITVN YRESYGMYAC 180
  181 NGILFNHESP RRGETFVTRK ITRAIANIAQ GLESCLYLGN MDSLRDWGHA KDYVKMQWMM 240
  241 LQQEQPEDFV IATGVQYSVR QFVEMAAAQL GIKLRFEGTG VEEKGIVVSV TGHDAPGVKP 300
  301 GDVIIAVDPR YFRPAEVETL LGDPTKAHEK LGWKPEITLR EMVSEMVAND LEAAKKHSLL 360
  361 KSHGYDVAIA LES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.69897
Match:	1db3A
Description:	GDP-mannose 4,6-dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-glucose 4-epimerase activity	2.13934644118967	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.03956654822048	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.82673050487418	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: