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View Structure Prediction Details

Protein: REL3_RAT
Organism: Rattus norvegicus
Length: 140 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for REL3_RAT.

Description E-value Query
Range
Subject
Range
gi|114675713 - gi|114675713|ref|XP_001171356.1| PREDICTED: similar to RLN3 [Pan troglodytes]
156.0 [0..9] [140..35]
gi|37181470 - gi|37181470|gb|AAQ88548.1| RLN3 [Homo sapiens]
155.0 [0..9] [140..35]
gi|109123679 - gi|109123679|ref|XP_001111219.1| PREDICTED: similar to relaxin 3 preproprotein [Macaca mulatta]
152.0 [0..11] [140..37]
REL3_PIG - Relaxin-3 OS=Sus scrofa GN=RLN3 PE=1 SV=1
145.0 [0..9] [140..12]
REL3_MOUSE - Relaxin-3 OS=Mus musculus GN=Rln3 PE=2 SV=1
gi|182888423 - gi|182888423|gb|AAI60232.1| Relaxin 3 [synthetic construct]
141.0 [0..22] [140..23]
gi|73986797 - gi|73986797|ref|XP_853484.1| PREDICTED: similar to relaxin 3 preproprotein [Canis familiaris]
140.0 [0..15] [140..17]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATRGLLLAS WALLGALVLQ AEARPAPYGV KLCGREFIRA VIFTCGGSRW RRADILAHDP  60
   61 LGEFFADGEA NTDHLASELD EAVGSSEWLA LTKSPQVFYG GRSSWQGSPG VVRGSRDVLA 120
  121 GLSSSCCEWG CSKSQISSLC 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.86
Match: 3lriA
Description: Insulin-like growth factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 4.31472496662749 bayes_pls_golite062009
growth factor activity 2.9715887364597 bayes_pls_golite062009
protein binding 2.54644812554184 bayes_pls_golite062009
binding 1.97432615074248 bayes_pls_golite062009
hormone activity 0.718799310596802 bayes_pls_golite062009
protein complex binding 0.63920351200841 bayes_pls_golite062009
insulin-like growth factor receptor binding 0.502074416905024 bayes_pls_golite062009
growth factor binding 0.401734283450917 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle