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View Structure Prediction Details

Protein: FGF5_MOUSE
Organism: Mus musculus
Length: 264 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FGF5_MOUSE.

Description E-value Query
Range
Subject
Range
FGF5_RAT - Fibroblast growth factor 5 OS=Rattus norvegicus GN=Fgf5 PE=2 SV=1
265.0 [0..1] [264..1]
gi|182545, gi|47... - ref|NP_004455.1| fibroblast growth factor 5 isoform 1 precursor [Homo sapiens], gi|182545|gb|AAB064...
248.0 [0..17] [264..17]
gi|114594027 - gi|114594027|ref|XP_526572.2| PREDICTED: similar to fibroblast growth factor-5 isoform 4 [Pan troglo...
248.0 [0..17] [264..17]
gi|114703726, gi... - gi|82623594|gb|ABB87177.1| fibroblast growth factor 5 [Canis familiaris], gi|114703726|ref|NP_001041...
240.0 [0..18] [264..18]
gi|109074356 - gi|109074356|ref|XP_001089996.1| PREDICTED: similar to Fibroblast growth factor 5 precursor (FGF-5) ...
CCDS34021.1_1 - null
233.0 [0..18] [264..18]
gi|76620189 - gi|76620189|ref|XP_616915.2| PREDICTED: similar to Fibroblast growth factor 5 precursor (FGF-5) (HBG...
219.0 [0..18] [264..232]

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Predicted Domain #1
Region A:
Residues: [1-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSLLFLIF CSHLIHSAWA HGEKRLTPEG QPAPPRNPGD SSGSRGRSSA TFSSSSASSP  60
   61 VAASPGSQGS GSEHSSFQWS PSGRRTGSLY CRVGIGFHLQ IYPDGKVNGS HEASVLSILE 120
  121 IFAVSQGIVG IRGVFSNKFL AMSKKGKLHA SAKFTDDCKF RERFQENSYN TYASAIHRTE 180
  181 KTGREWYVAL NKRGKAKRGC SPRVKPQHVS THFLPRFKQS EQPELSFTVT VPEKKKPPVK 240
  241 PKVPLSQPRR SPSPVKYRLK FRFG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.045757
Match: 1g82A
Description: Fibroblast growth factor 9, FGF9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fibroblast growth factor receptor binding 5.68976822724664 bayes_pls_golite062009
receptor binding 5.0880099372051 bayes_pls_golite062009
growth factor activity 4.94814294225946 bayes_pls_golite062009
cytokine activity 3.76931834545338 bayes_pls_golite062009
binding 1.9997408351526 bayes_pls_golite062009
protein binding 1.68839807849419 bayes_pls_golite062009
glycosaminoglycan binding 1.34255645304671 bayes_pls_golite062009
heparin binding 1.07853427694602 bayes_pls_golite062009
pattern binding 0.839280621598109 bayes_pls_golite062009
polysaccharide binding 0.67043430758093 bayes_pls_golite062009
nerve growth factor receptor binding 0.308245352535379 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle