YRC Public Data Repository - Protein Structure Prediction

Protein:	FGF9_MOUSE
Organism:	Mus musculus
Length:	208 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FGF9_MOUSE.

Description	E-value	Query Range	Subject Range
FGF9_PIG - Fibroblast growth factor 9 OS=Sus scrofa GN=FGF9 PE=2 SV=1	281.0	[0..1]	[208..1]
ENSOCUP000000006... - pep:novel chromosome:oryCun2:8:43047136:43084491:-1 gene:ENSOCUG00000000732 transcript:ENSOCUT000000... tr\|M3X6Y4\|M3X6Y4... - Fibroblast growth factor OS=Felis catus GN=FGF9 PE=3 SV=1 gi\|114648960 - gi\|114648960\|ref\|XP_001150741.1\| PREDICTED: fibroblast growth factor 9 [Pan troglodytes] gi\|73993421 - gi\|73993421\|ref\|XP_849938.1\| PREDICTED: similar to fibroblast growth factor 9 precursor isoform 2 [C... gi\|149730030 - gi\|149730030\|ref\|XP_001489747.1\| PREDICTED: similar to fibroblast growth factor 9 [Equus caballus] FGF9 - fibroblast growth factor 9 (glia-activating factor)	280.0	[0..1]	[208..1]
gi\|76631618, gi\|... - gi\|76631620\|ref\|XP_877779.1\| PREDICTED: similar to fibroblast growth factor 9 precursor isoform 2 [B...	280.0	[0..1]	[208..1]
gi\|45383362, gi\|... - gi\|45383362\|ref\|NP_989730.1\| fibroblast growth factor 9 (glia-activating factor) [Gallus gallus], gi...	280.0	[0..1]	[208..1]
FGF9_RAT - Fibroblast growth factor 9 OS=Rattus norvegicus GN=Fgf9 PE=2 SV=2 gi\|1488392 - gi\|1488392\|gb\|AAB36429.1\| fibroblast growth factor 9; FGF9 [Mus sp.] FGF9_MOUSE - Fibroblast growth factor 9 OS=Mus musculus GN=Fgf9 PE=2 SV=2	279.0	[0..1]	[208..1]
FGF9_DIDAL - Fibroblast growth factor 9 OS=Didelphis albiventris GN=FGF9 PE=2 SV=1	274.0	[0..1]	[208..1]
FGF9_XENLA - Fibroblast growth factor 9 OS=Xenopus laevis GN=fgf9 PE=2 SV=1	266.0	[0..1]	[208..1]
FGF20_MOUSE - Fibroblast growth factor 20 OS=Mus musculus GN=Fgf20 PE=2 SV=2	249.0	[0..1]	[208..1]

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Predicted Domain #1

Region A:
Residues: [1-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLGEVGSY FGVQDAVPFG NVPVLPVDSP VLLNDHLGQS EAGGLPRGPA VTDLDHLKGI  60
   61 LRRRQLYCRT GFHLEIFPNG TIQGTRKDHS RFGILEFISI AVGLVSIRGV DSGLYLGMNE 120
  121 KGELYGSEKL TQECVFREQF EENWYNTYSS NLYKHVDTGR RYYVALNKDG TPREGTRTKR 180
  181 HQKFTHFLPR PVDPDKVPEL YKDILSQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.045757
Match:	1ihkA
Description:	Fibroblast growth factor 9, FGF9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fibroblast growth factor receptor binding	5.68976822724664	bayes_pls_golite062009
growth factor activity	5.6790632853895	bayes_pls_golite062009
receptor binding	4.8109037277027	bayes_pls_golite062009
cytokine activity	3.76931834545338	bayes_pls_golite062009
protein binding	2.99442649109752	bayes_pls_golite062009
binding	2.90110516688922	bayes_pls_golite062009
glycosaminoglycan binding	2.49177421879896	bayes_pls_golite062009
heparin binding	2.1616134585534	bayes_pls_golite062009
polysaccharide binding	1.81686028727894	bayes_pls_golite062009
pattern binding	0.839280621598109	bayes_pls_golite062009
interleukin-1 receptor binding	0.8084616632765	bayes_pls_golite062009
nerve growth factor receptor binding	0.308245352535379	bayes_pls_golite062009
interleukin-1, Type I receptor binding	0.234893926720301	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: