YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM8A_MOUSE
Organism:	Mus musculus
Length:	97 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM8A_MOUSE.

Description	E-value	Query Range	Subject Range
TI8AB_MOUSE - Putative mitochondrial import inner membrane translocase subunit Tim8 A-B OS=Mus musculus GN=Timm8a2...	117.0	[0..1]	[97..1]
gi\|76660354 - gi\|76660354\|ref\|XP_600831.2\| PREDICTED: similar to translocase of inner mitochondrial membrane 8 hom...	112.0	[0..12]	[97..13]
TIM8A_BOVIN - Mitochondrial import inner membrane translocase subunit Tim8 A OS=Bos taurus GN=TIMM8A PE=3 SV=1 gi\|57112261 - gi\|57112261\|ref\|XP_538107.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 8 hom...	111.0	[0..1]	[97..1]
gi\|114689461, gi... - gi\|114689461\|ref\|XP_001139457.1\| PREDICTED: translocase of inner mitochondrial membrane 8 homolog A ... ENSCJAT00000009066 - null gi\|109131553 - gi\|109131553\|ref\|XP_001092722.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 8... TIMM8A - translocase of inner mitochondrial membrane 8 homolog A (yeast)	111.0	[0..1]	[97..1]
gi\|109072562 - gi\|109072562\|ref\|XP_001095067.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 8...	109.0	[0..9]	[97..51]
gi\|50745652 - gi\|50745652\|ref\|XP_420185.1\| PREDICTED: similar to X-linked deafness dystonia protein [Gallus gallus...	108.0	[0..4]	[97..1]
TIM8A_RAT - Mitochondrial import inner membrane translocase subunit Tim8 A OS=Rattus norvegicus GN=Timm8a PE=1 S...	107.0	[0..14]	[97..14]
TIM8A_DANRE - Mitochondrial import inner membrane translocase subunit Tim8 A OS=Danio rerio GN=timm8a PE=3 SV=1	103.0	[0..8]	[97..1]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESSTSSSGS ALGAVDPQLQ HFIEVETQKQ RFQQLVHQMT ELCWEKCMDK PGPKLDSRAE  60
   61 ACFVNCVERF IDTSQFILNR LEQTQKSKPV FSESLSD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.39794
Match:	2bskB
Description:	Crystal structure of the TIM9 Tim10 hexameric complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	6.14865333952665	bayes_pls_golite062009
macromolecule transmembrane transporter activity	6.14865333952665	bayes_pls_golite062009
protein transporter activity	3.96569591038426	bayes_pls_golite062009
protein transmembrane transporter activity	3.05578860381335	bayes_pls_golite062009
transporter activity	2.98936530239986	bayes_pls_golite062009
substrate-specific transporter activity	2.87815769573142	bayes_pls_golite062009
binding	1.95236231715199	bayes_pls_golite062009
transmembrane transporter activity	1.67782980643723	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.42890247609405	bayes_pls_golite062009
protein binding	1.35785935526536	bayes_pls_golite062009
primary active transmembrane transporter activity	1.15847548838424	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.15316743403707	bayes_pls_golite062009
active transmembrane transporter activity	1.10003802565492	bayes_pls_golite062009
unfolded protein binding	0.0997632819038001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: