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View Structure Prediction Details

Protein: NDUS8_MOUSE
Organism: Mus musculus
Length: 212 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDUS8_MOUSE.

Description E-value Query
Range
Subject
Range
gi|54611544 - gi|54611544|gb|AAH21616.2| NADH dehydrogenase (ubiquinone) Fe-S protein 8 [Mus musculus]
176.0 [0..1] [212..1]
gi|109463301, gi... - gi|27661165|ref|XP_215197.1| PREDICTED: similar to NADH dehydrogenase (ubiquinone) Fe-S protein 8 [R...
176.0 [0..1] [212..1]
NDUS8_MACFA - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Macaca fascicularis GN=NDUFS...
gi|109105179 - gi|109105179|ref|XP_001104103.1| PREDICTED: NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (N...
165.0 [0..1] [212..1]
gi|73982757 - gi|73982757|ref|XP_851642.1| PREDICTED: similar to NADH-ubiquinone oxidoreductase 23 kDa subunit, mi...
158.0 [0..1] [208..11]
gi|62897789 - gi|62897789|dbj|BAD96834.1| NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q r...
158.0 [0..1] [212..1]
gi|111661819 - gi|111661819|gb|ABH12161.1| mitochondrial complex I subunit NDUFS8 [Gorilla gorilla]
NDUS8_GORGO - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Gorilla gorilla gorilla GN=N...
156.0 [0..1] [212..1]
NDS8A_ARATH - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-A, mitochondrial OS=Arabidopsis thaliana GN=At...
154.0 [0..45] [212..55]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYRLSSSMLP RALAQAMRTG HLNGQSLHSS AVAATYKYVN KKEQESEVDM KSATDNAARI  60
   61 LMWTELIRGL GMTLSYLFRE PATINYPFEK GPLSPRFRGE HALRRYPSGE ERCIACKLCE 120
  121 AICPAQAITI EAEPRADGSR RTTRYDIDMT KCIYCGFCQE ACPVDAIVEG PNFEFSTETH 180
  181 EELLYNKEKL LNNGDKWEAE IAANIQADYL YR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.09691
Match: 2fug9
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADH dehydrogenase activity 12.5726198200461 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 11.5379710261128 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 11.4267068380664 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 10.7661444048967 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 10.0573871968611 bayes_pls_golite062009
oxidoreductase activity 5.95698221294919 bayes_pls_golite062009
electron carrier activity 5.42600867641421 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 4.00434209032307 bayes_pls_golite062009
iron-sulfur cluster binding 3.32581564966388 bayes_pls_golite062009
metal cluster binding 3.32581564966388 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 3.29174700910768 bayes_pls_golite062009
formate dehydrogenase activity 2.79579164562277 bayes_pls_golite062009
binding 0.850925220183928 bayes_pls_golite062009
catalytic activity 0.488483980994331 bayes_pls_golite062009
protein binding 0.122045589752402 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 0.115812441015069 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.0827182678048914 bayes_pls_golite062009

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