YRC Public Data Repository - Protein Structure Prediction

Protein:	GSTK1_MOUSE
Organism:	Mus musculus
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSTK1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109069349 - gi\|109069349\|ref\|XP_001087577.1\| PREDICTED: glutathione S-transferase kappa 1 [Macaca mulatta]	210.0	[0..1]	[226..1]
GSTK1 - glutathione S-transferase kappa 1	210.0	[0..1]	[226..1]
gi\|114616503 - gi\|114616503\|ref\|XP_519446.2\| PREDICTED: glutathione transferase kappa 1 isoform 5 [Pan troglodytes]	210.0	[0..1]	[226..1]
GSTK1_RAT - Glutathione S-transferase kappa 1 OS=Rattus norvegicus GN=Gstk1 PE=1 SV=3 gi\|1911749 - gi\|1911749\|gb\|AAB50831.1\| glutahione S-transferase subunit 13; rGSTK1 [Rattus sp.]	208.0	[0..1]	[226..1]
gi\|86826515, gi\|... - gi\|86826515\|gb\|AAI12480.1\| Glutathione S-transferase kappa 1 [Bos taurus], gi\|118601826\|ref\|NP_00107...	203.0	[0..1]	[226..1]
gi\|73978758 - gi\|73978758\|ref\|XP_532742.2\| PREDICTED: similar to Glutathione S-transferase kappa 1 (GST 13-13) (Gl...	202.0	[0..1]	[226..1]
gi\|23500321, gi\|... - gi\|23500321\|ref\|NP_699761.1\| frnE protein, putative [Brucella suis 1330], gi\|23463934\|gb\|AAN33766.1\|... gi\|17989035, gi\|... - gi\|17989035\|ref\|NP_541668.1\| FRNE [Brucella melitensis 16M], gi\|17984876\|gb\|AAL53932.1\| frne [Brucel... gi\|225686363, gi... - gi\|225686363\|ref\|YP_002734335.1\| DSBA oxidoreductase [Brucella melitensis ATCC 23457], gi\|225642468\|... gi\|148557851, gi... - gi\|148557851\|ref\|YP_001257566.1\| dsba oxidoreductase [Brucella ovis ATCC 25840], gi\|148369136\|gb\|ABQ... gi\|254699814 - gi\|254699814\|ref\|ZP_05161642.1\| DSBA oxidoreductase [Brucella suis bv. 5 str. 513] gi\|25367097 - pir\|\|AI3595 frnE protein [imported] - Brucella melitensis (strain 16M) gi\|225615569, gi... - gi\|225629073\|ref\|ZP_03787106.1\| FRNE [Brucella ceti str. Cudo], gi\|225615569\|gb\|EEH12618.1\| FRNE [Br... gi\|161337450, gi... - gi\|161620639\|ref\|YP_001594525.1\| DSBA oxidoreductase [Brucella canis ATCC 23365], gi\|161337450\|gb\|AB... gi\|254711154 - gi\|254711154\|ref\|ZP_05172965.1\| DSBA oxidoreductase [Brucella pinnipedialis B2/94] gi\|254702952 - gi\|254702952\|ref\|ZP_05164780.1\| DSBA oxidoreductase [Brucella suis bv. 3 str. 686] gi\|254705930 - gi\|254705930\|ref\|ZP_05167758.1\| DSBA oxidoreductase [Brucella pinnipedialis M163/99/10]	196.0	[0..1]	[225..1]
gi\|148235618, gi... - gi\|77748129\|gb\|AAI06345.1\| MGC130886 protein [Xenopus laevis], gi\|148235618\|ref\|NP_001089691.1\| hypo...	196.0	[0..1]	[219..1]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPAPRILEL FYDVLSPYSW LGFEVLCRYQ HLWNIKLQLR PTLIAGIMKD SGNQPPAMVP  60
   61 RKGQYIFKEI PLLKQFFQVP LNIPKDFFGE TVKKGSINAM RFLTTVSMEQ PEMLEKVSRE 120
  121 IWMRVWSRDE DITEYQSILA AAVKAGMSTA QAQHFLEKIS TQQVKNKLIE NTDAACKYGA 180
  181 FGLPTTVAHV DGKTYMLFGS DRLELLAYLL GEKWMGPVPP TANARL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.154902
Match:	1r4wA
Description:	Crystal structure of Mitochondrial class kappa glutathione transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutathione transferase activity	3.10261229787796	bayes_pls_golite062009
antioxidant activity	2.98988279939823	bayes_pls_golite062009
glutathione binding	2.53131331487579	bayes_pls_golite062009
glutathione peroxidase activity	2.45655797002775	bayes_pls_golite062009
peroxidase activity	2.09720157676308	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.09720157676308	bayes_pls_golite062009
oxidoreductase activity	1.66622364190158	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.44229450804826	bayes_pls_golite062009
disulfide oxidoreductase activity	0.713619215118063	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.15984522114548	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: