YRC Public Data Repository - Protein Structure Prediction

Protein:	BXDC2_MOUSE, BRI...
Organism:	Mus musculus
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BXDC2_MOUSE, BRI....

Description	E-value	Query Range	Subject Range
gi\|12833364 - gi\|12833364\|dbj\|BAB22497.1\| unnamed protein product [Mus musculus]	327.0	[0..1]	[276..1]
gi\|114600702 - gi\|114600702\|ref\|XP_517812.2\| PREDICTED: similar to Brix domain containing 2 [Pan troglodytes]	327.0	[0..1]	[276..52]
gi\|123982586, gi... - gi\|123997253\|gb\|ABM86228.1\| brix domain containing 2 [synthetic construct], gi\|123982586\|gb\|ABM83034... BRIX1 - BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	325.0	[0..1]	[276..78]
BRX1_BOVIN - Ribosome biogenesis protein BRX1 homolog OS=Bos taurus GN=BRIX1 PE=2 SV=1	323.0	[0..1]	[276..78]
gi\|109076914 - gi\|109076914\|ref\|XP_001089767.1\| PREDICTED: BRIX [Macaca mulatta]	322.0	[0..1]	[276..78]
BXDC2_PONPY - Brix domain-containing protein 2 - Pongo pygmaeus (Orangutan) BRX1_PONAB - Ribosome biogenesis protein BRX1 homolog OS=Pongo abelii GN=BRIX1 PE=2 SV=1	319.0	[0..1]	[276..78]
BRX1_RAT - Ribosome biogenesis protein BRX1 homolog OS=Rattus norvegicus GN=Brix1 PE=2 SV=1	318.0	[0..1]	[276..77]
gi\|27370947 - gi\|27370947\|gb\|AAH41554.1\| LOC398268 protein [Xenopus laevis]	285.0	[0..1]	[270..63]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDLRMLMPH SKADTKMDRK DKLFVINEVC EMKNCNKCIY FEAKKKQDLY MWLSNSPHGP  60
   61 SAKFLVQNIH TLAELKMTGN CLKGSRPLLS FDPAFDDLPH YALLKEFLIQ IFSTPRYHPK 120
  121 SQPFVDHVFT FTILDNRIWF RNFQIIEEDA ALVEIGPRFV LNLIKIFQGS F

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.44
Match:	2cxhA
Description:	Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.323890296968392	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [172-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGPTLYENPH YQSPNMHRRV IRSITAAKYR ERQQVKDVQK LRKKEPKTIL PHDPTADVFV  60
   61 IPAEEKPVEI QWVKPEPKVD LKARKRRIYK RHRKLQQKMS RGSAK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.496	N/A	N/A	a.60.1	SAM/Pointed domain
View	Download	0.476	N/A	N/A	a.118.11	Cytochrome c oxidase subunit E
View	Download	0.440	N/A	N/A	a.60.2	RuvA domain 2-like
View	Download	0.417	N/A	N/A	a.60.1	SAM/Pointed domain
View	Download	0.415	N/A	N/A	a.60.2	RuvA domain 2-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: